Rali Aniket S, Patel Het, Lander Matthew M, Brennan Kaitlyn, Trahanas John, Schlendorf Kelly, Lindenfeld JoAnn, Kanwar Manreet
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.
JHLT Open. 2024 Nov 28;7:100180. doi: 10.1016/j.jhlto.2024.100180. eCollection 2025 Feb.
Under the revised UNOS heart allocation system, waitlist and post-transplant outcomes among patients bridged to transplant with VA-ECMO (BTT-ECMO) have improved. However, it remains largely unknown if these early trends have persisted over time. We queried the UNOS database for all adult heart-only BTT-ECMO recipients between January 2019 and December 2022. Our analysis shows that under the revised system, waitlist mortality and 1-year post-transplant outcomes have remained favorable, despite increased utilization of BTT-ECMO. This finding supports the original intent of the revised allocation system in ensuring more rapid transplantation of the sickest patients while avoiding a higher post-HT mortality.
在修订后的器官共享联合网络(UNOS)心脏分配系统下,通过体外膜肺氧合(VA-ECMO)过渡到移植的患者在等待名单上的情况以及移植后的结局有所改善。然而,这些早期趋势是否随着时间的推移而持续,在很大程度上仍然未知。我们查询了UNOS数据库中2019年1月至2022年12月期间所有仅接受心脏移植且通过VA-ECMO过渡的成年患者。我们的分析表明,在修订后的系统下,尽管VA-ECMO的使用增加,但等待名单上的死亡率和移植后1年的结局仍然良好。这一发现支持了修订后分配系统的初衷,即确保病情最严重的患者能够更快地接受移植,同时避免移植后更高的死亡率。