Schleich Marianne, Galvin John J, Micaletti Fabrice, Bakhos David
University Hospital of Tours, Department of Otolaryngology - Head and Neck Surgery, Tours, France.
House Institute Foundation, Los Angeles, California, United States of America; University Hospital of Tours, Tours, France.
Braz J Otorhinolaryngol. 2025 Mar 26;91(4):101584. doi: 10.1016/j.bjorl.2025.101584.
Electrocochleography (ECOG) is a composite objective measure of the cochlea and the cochlear nerve responses. The objectives of this study were to investigate the evolution of ECOG after cochlear implantation and compare them with audiometric thresholds over a 12-month period.
A prospective monocentric study was conducted in Advanced Bionics cochlear implant recipients. Audiometric thresholds were recorded preoperatively and at 1-, 3-, 6-, and 12-months post cochlear implantation; ECOGs were recorded perioperatively after the electrode array insertion and at 1-, 3-, 6-, and 12-months post cochlear implantation. Cochlear Microphonic (CM) responses were measured by an apical electrode of the cochlear implant. Postoperative behavioral and ECOG thresholds were compared using Pearson correlation analyses.
A total of 17 patients were included. At 1-year, residual hearing (≤90 dB HL at 500 Hz) was preserved for 4 out of 17 patients. Significant correlations were observed between perioperative ECOG and preoperative audiometric thresholds (p = 0.008), and between ECOG and audiometric thresholds at 3-months postoperative (p = 0.002).
ECOG can reflect changes in cochlear responses during and after implantation and may help to predict deterioration of residual hearing.
Level 3.
电耳蜗描记术（ECOG）是一种对耳蜗及耳蜗神经反应的综合客观测量方法。本研究的目的是调查人工耳蜗植入术后ECOG的变化情况，并在12个月的时间内将其与听力阈值进行比较。
对接受先进生物电子公司人工耳蜗植入的患者进行了一项前瞻性单中心研究。在术前以及人工耳蜗植入术后1个月、3个月、6个月和12个月记录听力阈值；在电极阵列插入术后围手术期以及人工耳蜗植入术后1个月、3个月、6个月和12个月记录ECOG。通过人工耳蜗的顶端电极测量耳蜗微音电位（CM）反应。使用Pearson相关分析比较术后行为学阈值和ECOG阈值。
共纳入17例患者。1年后，17例患者中有4例保留了残余听力（500Hz时≤90dB HL）。围手术期ECOG与术前听力阈值之间（p = 0.008）以及术后3个月时ECOG与听力阈值之间（p = 0.002）观察到显著相关性。
ECOG可以反映植入过程中和植入后耳蜗反应的变化，并且可能有助于预测残余听力的恶化。
3级。
