García Miguel M J, García-Alix Pérez A, de José Gómez M I, Barea Blanco I, Vidal López M L, García Hortelano J
An Esp Pediatr. 1985 Apr 15;22(5):353-8.
Due to an increase in the number of cases of spotted fever, a prospective study was undertaken in 31 children affected by the disease, including clinical, laboratory and microbiological data from may to october of 1983. The most frequent symptoms found were: fever 100%, "tache noire" 87%, and a maculopapular rash 81%. The Weil-Felix reaction was positive in 65% of them and indirect immunofluorescence was positive in 81%, confirming the sensitivity and specificity of this serologic procedure. The 27 children who received specific treatment, 26 with tetracycline and one with chloramphenicol, differed considerably in a lesser duration of their symptoms, in comparison with the group of children without treatment.
由于斑疹热病例数量增加,对31名患该病的儿童进行了一项前瞻性研究,包括1983年5月至10月的临床、实验室和微生物学数据。发现最常见的症状是:发热100%,“黑色斑点”87%,斑丘疹81%。外斐反应在65%的病例中呈阳性,间接免疫荧光在81%的病例中呈阳性,证实了该血清学检测方法的敏感性和特异性。与未接受治疗的儿童组相比,接受特殊治疗的27名儿童(26名用四环素治疗,1名用氯霉素治疗)症状持续时间明显较短。