López Parés P, Muñoz Espín T, Espejo Arenas E, Font Creus B, Segura Porta F, Martínez Vila I, Travería Casanova J, Bella Cueto F
Hospital de San Lázaro, Tarrasa, Barcelona.
An Esp Pediatr. 1988 Apr;28(4):293-6.
Authors present a prospective study of 130 cases of Mediterranean spotted fever treated between 1983 and 1985 in two Departments of Paediatrics of the Valles Occidental, area near Barcelona. Thirty-eight percent of the children came from suburban areas, an urban areas, an urban or rural origin being less frequent. Previous contacts with dogs existed in 86% of the cases. Most frequent clinical signs were fever (100%) maculo-papular rash (97%) and arthromyalgias (70%). The "tache noire" was found in 87% of the cases. Presence of arthritis in two patients is underlined. Indirect immunofluorescence to Rickettsia conorii was positive (much greater than 1/40) in 75% of the cases. All patients improved after treatment with tetracycline or erythromycin. There were no relapse.
作者对1983年至1985年间在巴塞罗那附近的西瓦列斯地区两个儿科部门接受治疗的130例地中海斑疹热病例进行了前瞻性研究。38%的儿童来自郊区,来自城市或农村的情况较少见。86%的病例此前与狗有过接触。最常见的临床症状是发热(100%)、斑丘疹(97%)和关节痛(70%)。87%的病例出现“黑色斑疹”。强调了两名患者出现关节炎。对康氏立克次体的间接免疫荧光检测在75%的病例中呈阳性(远高于1/40)。所有患者在接受四环素或红霉素治疗后病情好转。无复发情况。