Revalska Miglena, Radkova Mariana, Zhiponova Miroslava, Vassileva Valya, Iantcheva Anelia
AgroBioInstitute, Agricultural Academy, Blvd. Dragan Tsankov 8, 1164 Sofia, Bulgaria.
Department of Plant Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov blvd., 1164 Sofia, Bulgaria.
Genes (Basel). 2025 Feb 28;16(3):296. doi: 10.3390/genes16030296.
Members of the Leguminosae family are important crops that provide food, animal feed and vegetable oils. Legumes make a substantial contribution to sustainable agriculture and the nitrogen cycle through their unique ability to fix atmospheric nitrogen in agricultural ecosystems. Over the past three decades, and have emerged as model plants for genomic and physiological research in legumes. The advancement of innovative molecular and genetic tools, particularly insertional mutagenesis using the retrotransposon , has facilitated the development of extensive mutant collections and enabled precise gene tagging in plants for the identification of key symbiotic and developmental genes. Building on these resources, twelve years ago, our research team initiated the establishment of a platform for functional genomic studies of legumes in Bulgaria. In the framework of this initiative, we conducted systematic sequencing of selected mutant lines and identified genes involved in plant growth and development for detailed functional characterization. This review summarizes our findings on the functions of selected genes involved in the growth and development of the model species, discusses the molecular mechanisms underlying important developmental processes and examines the potential for the translation of this fundamental knowledge to improve commercially important legume crops in Bulgaria and globally.
豆科植物是重要的作物，可提供食物、动物饲料和植物油。豆类通过其在农业生态系统中固定大气氮的独特能力，为可持续农业和氮循环做出了重大贡献。在过去三十年中，[两种植物名称未给出]已成为豆类基因组和生理学研究的模式植物。创新分子和遗传工具的进步，特别是使用反转录转座子[具体名称未给出]的插入诱变，促进了大量突变体库的开发，并能够在植物中进行精确的基因标记，以鉴定关键的共生和发育基因。基于这些资源，十二年前，我们的研究团队开始在保加利亚建立一个豆类功能基因组研究平台。在该计划的框架内，我们对选定的突变系进行了系统测序，并鉴定了参与植物生长和发育的基因，以进行详细的功能表征。本综述总结了我们对模式物种生长和发育中选定基因功能的研究结果，讨论了重要发育过程的分子机制，并探讨了将这些基础知识转化为改善保加利亚和全球商业上重要豆类作物的潜力。
