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真空干预后剖宫产瘢痕组织的组织弹性和疼痛压力阈值的即时变化:一项开放性临床试验。

Immediate Changes in the Elasticity of Tissue and the Pain Pressure Threshold in Cesarean Scar Tissue After a Vacuum Intervention: An Open Clinical Trial.

作者信息

González-Muñoz Ana, Navarro-Ledesma Santiago

机构信息

Clinical Medicine and Public Health PhD Program, Faculty of Health Sciences, University of Granada, Av. de la Ilustración, 60, 18071 Granada, Spain.

Clínica Actium, Avenida Hernán Núñez de Toledo 6, 29018 Málaga, Spain.

出版信息

Biomedicines. 2025 Feb 21;13(3):557. doi: 10.3390/biomedicines13030557.

DOI:10.3390/biomedicines13030557
PMID:40149534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11939837/
Abstract

: Cesarean section (C-section) scars are commonly linked to reduced tissue elasticity and increased pain due to adhesion formation. Addressing these concerns is essential to improving patient comfort and functional outcomes. This study aimed to assess the immediate effects of vacuum therapy on skin elasticity and pain sensitivity in C-section scar tissue. : Thirty-one women with C-section scars older than six months and less than two years participated in an open clinical trial. The skin elasticity was assessed using the Adheremeter, and the pain sensitivity was measured through the Pressure Pain Threshold (PPT) using algometry. The intervention consisted of a 15 min vacuum therapy session using the AeroFlow device that targeted the scar and surrounding areas. : The vacuum therapy intervention resulted in significant improvements in the skin elasticity at multiple assessment points, particularly in regions with fascial restrictions ( < 0.05). Concurrently, the PPT values decreased, indicating a reduction in pain sensitivity around the scar area ( < 0.05). These findings suggest that vacuum therapy may enhance tissue flexibility and alleviate pain in adherent C-section scars. : This study demonstrated the potential of vacuum therapy as an effective intervention to improve skin elasticity and reduce pain sensitivity in C-section scars. The Adheremeter-based assessment provided valuable insights into the biomechanical properties of scar tissue and supported its use in scar management protocols. This approach offers a promising, non-invasive strategy for personalized scar treatment, ultimately aiming to enhance patient outcomes and quality of life.

摘要

剖宫产(C 形切口)疤痕通常与组织弹性降低和因粘连形成导致的疼痛加剧有关。解决这些问题对于提高患者舒适度和功能预后至关重要。本研究旨在评估真空疗法对剖宫产疤痕组织皮肤弹性和疼痛敏感性的即时影响。

31 名剖宫产疤痕形成时间超过 6 个月且不到 2 年的女性参与了一项开放性临床试验。使用粘附仪评估皮肤弹性,并通过使用压力痛觉计测量压力痛阈(PPT)来测定疼痛敏感性。干预措施包括使用 AeroFlow 设备对疤痕及其周围区域进行 15 分钟的真空疗法治疗。

真空疗法干预在多个评估点均使皮肤弹性得到显著改善,尤其是在存在筋膜限制的区域(P<0.05)。同时,PPT 值降低,表明疤痕区域周围的疼痛敏感性降低(P<0.05)。这些发现表明,真空疗法可能会增强粘连性剖宫产疤痕的组织柔韧性并减轻疼痛。

本研究证明了真空疗法作为一种有效干预措施,可改善剖宫产疤痕的皮肤弹性并降低疼痛敏感性的潜力。基于粘附仪的评估为疤痕组织的生物力学特性提供了有价值的见解,并支持其在疤痕管理方案中的应用。这种方法为个性化疤痕治疗提供了一种有前景的非侵入性策略,最终目标是改善患者预后和生活质量。

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本文引用的文献

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Healthcare (Basel). 2024 Oct 31;12(21):2166. doi: 10.3390/healthcare12212166.
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Roles of Mechanosensitive Channel Piezo1 in Wound Healing and Scar Formation.机械敏感通道Piezo1在伤口愈合和瘢痕形成中的作用
Life (Basel). 2024 Mar 13;14(3):377. doi: 10.3390/life14030377.
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The effectiveness of hysteroscopy for the treatment of cesarean scar pregnancy: a retrospective cohort study.
宫腔镜治疗剖宫产瘢痕妊娠的有效性:一项回顾性队列研究。
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Association between elasticity of tissue and pain pressure threshold in the tender points present in subjects with fibromyalgia: a cross-sectional study.纤维肌痛患者压痛敏感点组织弹性与疼痛压力阈值的相关性:一项横断面研究。
Sci Rep. 2023 Dec 12;13(1):22003. doi: 10.1038/s41598-023-49550-y.
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Roles of negative pressure wound therapy for scar revision.负压伤口治疗在瘢痕修复中的作用。
Front Physiol. 2023 Oct 12;14:1194051. doi: 10.3389/fphys.2023.1194051. eCollection 2023.
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