Holborn Tayler, Schifano Fabrizio, Smith Emma, Deluca Paolo
Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, London SE5 8AF, UK.
School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Brain Sci. 2025 Mar 10;15(3):292. doi: 10.3390/brainsci15030292.
Numerous individuals suffer from attentional issues, such as ADHD. While medication is considered the first-line treatment, it is unavailable to some. As a result, certain individuals are choosing to self-medicate with novel stimulants, a phenomenon that remains poorly understood. We aimed to investigate which NPSs are being used to self-medicate ADHD, evaluate their perceived effectiveness, and explore the experiences and motivations of those self-medicating.
Data from respondents ( = 225) (mean age [SD] = 29.5 ± 9.6; male = 83%; female = 12%; non-binary = 5%) were collected via an online survey, with nine participants (mean age = 31.4; male = 5; female = 1; non-binary = 3) undertaking further semi-structured interviews and the data being investigated using a framework analysis.
The most-used NPSs were 4F-MPH and 2-FMA. Some individuals perceived self-medication to be more effective than conventional treatment ( < 0.001). A framework analysis identified the following themes surrounding novel stimulant self-medication: (1) the use of NPS stimulants as a stopgap between treatments; (2) poor access to ADHD treatment; (3) a lack of openness and confidence in psychiatrists and healthcare providers.
Novel stimulants are being used when access to ADHD treatment is poor. Interventions should aim to reduce long treatment wait times and issues surrounding geographical access. Careful consideration should be given before denying stimulant medication to individuals with co-occurring substance use and psychiatric comorbidity. Individuals desire a more patient-centred ADHD treatment with broader pharmacotherapies.
许多人存在注意力方面的问题,如注意缺陷多动障碍(ADHD)。虽然药物治疗被视为一线治疗方法,但对一些人来说无法获得。因此,一些人选择使用新型兴奋剂进行自我治疗,这一现象仍未得到充分理解。我们旨在调查哪些新型精神活性物质(NPSs)被用于ADHD的自我治疗,评估其感知到的有效性,并探索那些自我治疗者的经历和动机。
通过在线调查收集了225名受访者的数据(平均年龄[标准差]=29.5±9.6岁;男性=83%;女性=12%;非二元性别=5%),9名参与者(平均年龄=31.4岁;男性=5名;女性=1名;非二元性别=3名)进行了进一步的半结构化访谈,并使用框架分析对数据进行研究。
最常使用的NPSs是4F-甲基苯丙胺(4F-MPH)和2-氟甲基苯丙胺(2-FMA)。一些人认为自我治疗比传统治疗更有效(P<0.001)。框架分析确定了围绕新型兴奋剂自我治疗的以下主题:(1)将NPS兴奋剂用作治疗间隙的手段;(2)ADHD治疗的可及性差;(3)对精神科医生和医疗服务提供者缺乏开放性和信心。
在ADHD治疗可及性差时会使用新型兴奋剂。干预措施应旨在减少长期的治疗等待时间以及地理可及性方面的问题。在拒绝给同时存在物质使用和精神共病的个体使用兴奋剂药物之前应谨慎考虑。个体希望获得更以患者为中心的ADHD治疗以及更广泛的药物治疗方法。