Graves W G, Martinez M J, Carter P L, Barry M J, Clarke J S
Ann Thorac Surg. 1985 Jul;40(1):57-9. doi: 10.1016/s0003-4975(10)61170-8.
Forty-one patients underwent operative staging for bronchogenic carcinoma following computed tomography of the mediastinum between August, 1982, and March, 1984. Twenty-seven patients were classified as Stage I preoperatively; in 2 of them, positive mediastinal nodes were found at thoracotomy. For the 14 patients in whom positive nodes had been identified by computed tomographic (CT) scanning, staging was unchanged as a result of the findings at mediastinoscopy or thoracotomy or both. In this series, computed tomography had a sensitivity of 89%, a specificity of 100%, and an overall accuracy rate of 95%. We conclude that mediastinoscopy is not needed in patients without evidence of mediastinal nodal enlargement by CT scan; when performed, it should be guided toward those nodes identified as positive.
1982年8月至1984年3月期间,41例患者在进行纵隔计算机断层扫描后接受了支气管源性癌的手术分期。27例患者术前被归类为I期;其中2例在开胸手术时发现纵隔淋巴结阳性。对于14例经计算机断层扫描(CT)发现淋巴结阳性的患者,纵隔镜检查或开胸手术或两者的检查结果并未改变分期。在本系列中,计算机断层扫描的敏感性为89%,特异性为100%,总体准确率为95%。我们得出结论,对于CT扫描未显示纵隔淋巴结肿大的患者,无需进行纵隔镜检查;如果进行纵隔镜检查,应针对那些被确定为阳性的淋巴结。