Blazer D, George L K, Landerman R, Pennybacker M, Melville M L, Woodbury M, Manton K G, Jordan K, Locke B
Arch Gen Psychiatry. 1985 Jul;42(7):651-6. doi: 10.1001/archpsyc.1985.01790300013002.
We studied rural/urban differences in the prevalence of nine psychiatric disorders from a community survey (part of the Epidemiologic Catchment Area Program) of 3,921 adults living in the Piedmont of North Carolina. Crude comparisons disclosed that major depressive episodes and drug abuse and/or dependence were more common in the urban area, whereas alcohol abuse/dependence was more common in the rural area. When prevalence for these disorders was stratified for age, sex, race, and education (factors that may confound urban/rural comparisons), a number of significant differences were identified, such as higher prevalence of major depression in female and white subjects and higher prevalence of alcohol abuse/dependence in the less educated subjects. A logistic-regression analysis was used to determine if significant urban/rural differences persisted when these potential confounders were controlled. Major depressive disorders were found to be twice as frequent in the urban area in this controlled analysis.
我们通过对居住在北卡罗来纳州皮埃蒙特的3921名成年人进行社区调查(流行病学集水区项目的一部分),研究了九种精神疾病患病率的城乡差异。粗略比较显示,重度抑郁发作以及药物滥用和/或依赖在城市地区更为常见,而酒精滥用/依赖在农村地区更为常见。当按年龄、性别、种族和教育程度(可能混淆城乡比较的因素)对这些疾病的患病率进行分层时,发现了一些显著差异,例如女性和白人受试者中重度抑郁症的患病率较高,以及受教育程度较低的受试者中酒精滥用/依赖的患病率较高。使用逻辑回归分析来确定在控制这些潜在混杂因素后,城乡之间是否仍然存在显著差异。在这项对照分析中,发现城市地区重度抑郁症的发病率是农村地区的两倍。