Hussain Usama, Ziauddeen Nida, Taylor Elizabeth, Alwan Nisreen A
Royal Berkshire Hospital, Reading, UK.
School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK.
Curr Obes Rep. 2025 Mar 28;14(1):27. doi: 10.1007/s13679-025-00617-z.
This review investigates the relationship of paternal smoking and overweight/obesity during pregnancy and up to one-year post-birth with childhood overweight/obesity up to age 12. Both exposures were analysed separately and together, if appropriate.
Included studies indicate that paternal overweight/obesity is consistently associated with increased risk of childhood overweight/obesity, suggesting a robust intergenerational link. Conversely, findings on paternal smoking are less consistent. Five out of six studies suggest that paternal smoking during pregnancy may contribute to increased risk but one found no association. Children of fathers with overweight/obesity are at higher risk of overweight/obesity in childhood. Paternal smoking was associated with higher risk of child overweight/obesity in most studies. Trajectories of overweight and obesity are likely to be transgenerational and systemic changes to tackle their socioeconomic determinants may be required to address these.
本综述调查孕期及产后一年内父亲吸烟及超重/肥胖与12岁前儿童超重/肥胖之间的关系。如有必要，将分别及综合分析这两种暴露因素。
纳入研究表明，父亲超重/肥胖始终与儿童超重/肥胖风险增加相关，提示存在强大的代际联系。相反，关于父亲吸烟的研究结果不太一致。六项研究中有五项表明孕期父亲吸烟可能导致风险增加，但有一项研究未发现关联。父亲超重/肥胖的孩子在儿童期超重/肥胖的风险更高。大多数研究中，父亲吸烟与儿童超重/肥胖风险较高相关。超重和肥胖的轨迹可能具有代际性，可能需要进行系统性改变以解决其社会经济决定因素，从而应对这些问题。
