Cai Lijun, Yuan Wenying
Department of Pediatric Gastroenterology, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei Province, China.
Department of Pediatric, Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei Province, China.
Medicine (Baltimore). 2025 Mar 28;104(13):e41741. doi: 10.1097/MD.0000000000041741.
This study aimed to explore the influence of emotional factors on the efficacy and prognosis of endoscopic treatment in children with functional abdominal pain (FAP), and to identify related risk factors. A total of 66 children with FAP treated with endoscopy from January 2018 to June 2024 were evaluated using the Child Depression Scale, Child Anxiety Scale, Quality of Life Scale, and visual analog scoring. Patients' demographics, clinical symptoms, treatment methods, and outcomes were recorded. Symptom remission, recurrence rates, and quality of life changes were compared after 6 months. Pearson correlation and logistic regression analyses were conducted. High-anxiety (35 cases) and low-anxiety (31 cases) groups had mean pain scores of 4.85 ± 1.21 and 2.10 ± 0.85, respectively (P = .001). Recurrence rates were 34.3% and 9.7%, respectively (P = .012). Good-mood (20 cases) and bad-mood (46 cases) groups had quality of life scores of 85.50 ± 5.50 and 63.50 ± 7.00 (P < .05). High-depression (25 cases) and low-depression (41 cases) groups had mean pain scores of 5.10 ± 1.10 and 2.40 ± 0.75 (P < .05), with recurrence rates of 36.0% and 14.6%, respectively (P = .009). Anxiety and depression were positively correlated with pain scores (r = 0.60, r = 0.58, P < .05) and negatively correlated with quality of life (r = -0.56, r = -0.54, P < .05). Anxiety (OR = 3.20, P = .003) and depression (OR = 2.80, P = .007) were independent risk factors for recurrence. Emotional factors significantly affect the efficacy and prognosis of endoscopic treatment in children with FAP. Negative emotions increase recurrence risk and reduce treatment efficacy and quality of life. Psychological intervention should be considered to improve outcomes.
本研究旨在探讨情绪因素对功能性腹痛（FAP）患儿内镜治疗疗效及预后的影响，并识别相关危险因素。对2018年1月至2024年6月期间接受内镜治疗的66例FAP患儿，使用儿童抑郁量表、儿童焦虑量表、生活质量量表和视觉模拟评分进行评估。记录患者的人口统计学资料、临床症状、治疗方法及结局。比较6个月后的症状缓解情况、复发率及生活质量变化。进行Pearson相关性分析和Logistic回归分析。高焦虑组（35例）和低焦虑组（31例）的平均疼痛评分分别为4.85±1.21和2.10±0.85（P = 0.001）。复发率分别为34.3%和9.7%（P = 0.012）。情绪好组（20例）和情绪差组（46例）的生活质量评分分别为85.50±5.50和63.50±7.00（P < 0.05）。高抑郁组（25例）和低抑郁组（41例）的平均疼痛评分分别为5.10±1.10和2.40±0.75（P < 0.05），复发率分别为36.0%和14.6%（P = 0.009）。焦虑和抑郁与疼痛评分呈正相关（r = 0.60，r = 0.58，P < 0.05），与生活质量呈负相关（r = -0.56，r = -0.54，P < 0.05）。焦虑（OR = 3.20，P = 0.003）和抑郁（OR = 2.80，P = 0.007）是复发的独立危险因素。情绪因素显著影响FAP患儿内镜治疗的疗效及预后。负面情绪会增加复发风险，降低治疗效果和生活质量。应考虑进行心理干预以改善结局
