Moazam F, Talbert J L
Arch Surg. 1985 Jul;120(7):856-9. doi: 10.1001/archsurg.1985.01390310088020.
Since 1973, seven infants treated at the University of Florida, Gainesville, for congenital anorectal anomalies have been found to have concomitant sacrococcygeal teratomas. As anorectal anomalies occur in approximately one in every 5,000 live births and sacrococcygeal teratomas are noted in one in every 40,000 live births, this presentation would suggest a prevalence that precludes a random association. The presence of significant anorectal strictures in these patients resulted in a delay in the diagnosis of the presacral teratomas. As the frequency of malignant change in sacrococcygeal teratomas has been documented to increase proportionately with age, early diagnosis and excision of these lesions is essential. Our experience with these children suggests that the presence of congenital anorectal malformations in infancy should raise the physician's index of suspicion for associated sacrococcygeal teratomas.
自1973年以来，在佛罗里达大学盖恩斯维尔分校接受先天性肛肠畸形治疗的七名婴儿被发现同时患有骶尾部畸胎瘤。由于肛肠畸形在每5000例活产中约有1例发生，而骶尾部畸胎瘤在每40000例活产中约有1例被发现，这种情况表明其发生率排除了随机关联。这些患者中严重肛肠狭窄的存在导致了骶前畸胎瘤诊断的延迟。由于骶尾部畸胎瘤恶变的频率已被证明与年龄成比例增加，早期诊断和切除这些病变至关重要。我们对这些儿童的经验表明，婴儿期先天性肛肠畸形的存在应提高医生对相关骶尾部畸胎瘤的怀疑指数。
