Yılmaz Güleser Güney, Tanrıverdi Müberra, Doğan Remzi, Özturan Orhan
Department of Occupational Therapy, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey.
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bezmialem Vakıf University, İstanbul, Turkey.
Mult Scler Relat Disord. 2025 May;97:106387. doi: 10.1016/j.msard.2025.106387. Epub 2025 Mar 20.
This study aims to evaluate neurogenic dysphagia in individuals with various neurological disorders.
A prospective cross-sectional study was conducted adults with Multiple Sclerosis (MS), stroke, or Parkinson's Disease (PD) who presented with dysphagia. Assessments included the Functional Oral Intake Scale (FOIS) for dietary status, the Flexible Endoscopic Evaluation of Swallowing (FEES) with Penetration-Aspiration Scale (PAS) for swallowing function, and the Eating Assessment Tool (EAT-10) and Swallow Quality of Life Questionnaire (SWAL-QOL) for dysphagia severity and swallowing/eating-related quality of life (SRQoL), respectively. Statistical analyses included ANOVA.
The study included 105 participants with MS, stroke, and PD groups. SWAL-QOL scores were significantly higher in the MS and PD groups compared to the stroke group (p = 0.001). Stroke patients had the most severe overall swallowing difficulties, while MS patients experienced the highest rate of aspiration (37 %). Fatigue levels were significantly higher in the MS and PD groups (p = 0.001), and social function scores were lowest in the stroke group (p = 0.041). No significant differences were observed in eating desire, fear of eating, sleep quality, communication, or EAT-10 scores across the groups.
This study highlights the differential impact of neurogenic dysphagia on swallowing function and SRQoL. Although dysphagia is a known issue in acute neurological conditions such as strokes, individuals with progressive diagnoses such as MS should be referred to swallowing clinics at an early stage, keeping in mind that it can lead to serious consequences that can affect their quality of life.
本研究旨在评估患有各种神经系统疾病的个体的神经性吞咽困难。
对患有吞咽困难的多发性硬化症（MS）、中风或帕金森病（PD）成人进行了一项前瞻性横断面研究。评估包括用于饮食状况的功能性口服摄入量表（FOIS）、用于吞咽功能的带有渗透-误吸量表（PAS）的柔性内镜吞咽评估（FEES），以及分别用于吞咽困难严重程度和吞咽/进食相关生活质量（SRQoL）的进食评估工具（EAT-10）和吞咽生活质量问卷（SWAL-QOL）。统计分析包括方差分析。
该研究纳入了105名参与者，分为MS、中风和PD组。与中风组相比，MS组和PD组的SWAL-QOL得分显著更高（p = 0.001）。中风患者总体吞咽困难最严重，而MS患者误吸发生率最高（37%）。MS组和PD组的疲劳水平显著更高（p = 0.001），中风组的社会功能得分最低（p = 0.041）。各组在进食欲望、进食恐惧、睡眠质量、沟通或EAT-10得分方面未观察到显著差异。
本研究强调了神经性吞咽困难对吞咽功能和SRQoL的不同影响。尽管吞咽困难在中风等急性神经系统疾病中是一个已知问题，但对于MS等进行性诊断的个体，应尽早转诊至吞咽诊所，要记住它可能导致严重后果，影响他们的生活质量。
