Liu Hongyu, Wang Xinquan, Zhao Huiyu, Liu Zhenzhen, Qi Peipei, Wang Zhiwei, Gu Chengbo, Di Shanshan
Key Laboratory of Forest Plant Ecology-Ministry of Education, Engineering Research Center of Forest Bio-Preparation-Ministry of Education, Heilongjiang Provincial Key Laboratory of Ecological Utilization of Forestry-based active substances, College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, PR China; State Key Laboratory of Agricultural Products Safety/ Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang, Institute of Agro-product Safety and Nutrition, Academy of Agricultural Sciences, Zhejiang, Hangzhou 310021, PR China.
State Key Laboratory of Agricultural Products Safety/ Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang, Institute of Agro-product Safety and Nutrition, Academy of Agricultural Sciences, Zhejiang, Hangzhou 310021, PR China; Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Hangzhou 310021, PR China.
Food Chem. 2025 Jul 30;481:143943. doi: 10.1016/j.foodchem.2025.143943. Epub 2025 Mar 22.
The stereoselective behavior and dietary risk of bitertanol in four vegetables and soil were studied. Firstly, the method for measuring bitertanol stereoisomers by SFC-MS/MS was established and optimized, and the analysis time was 5 min. In addition, cis-(+)-(1R,2S)-bitertanol and trans-(+)-(1R,2R)-bitertanol were preferentially dissipated in cabbage and pakchoi, while trans-(+)-(1S,2S)-bitertanol had a preferential dissipation in lettuce. For diastereoisomers, cis-bitertanol was dissipated with preference in the vegetables under test. The dissipation halflives of rac-bitertanol were as follows: pakchoi (0.57-0.74 days) < cabbage (0.87-1.07 days) < celery (1.32-1.63 days) < lettuce (1.75-2.37 days) < soil (22.5-24.7 days). Finally, the final residual concentrations of rac-bitertanol in lettuce (0.0128 mg/kg) and celery (0.0289 mg/kg) were higher than the maximum residue limit (MRL, 0.01 mg/kg), which should raise concern. The results of dietary risk assessment showed that both the chronic dietary risk and the acute dietary risk of rac-bitertanol in these test vegetables were negligible.
研究了联苯三唑醇在四种蔬菜及土壤中的立体选择性行为和膳食风险。首先，建立并优化了超临界流体色谱-串联质谱法（SFC-MS/MS）测定联苯三唑醇立体异构体的方法，分析时间为5分钟。此外，顺式-(+)-(1R,2S)-联苯三唑醇和反式-(+)-(1R,2R)-联苯三唑醇在白菜和小白菜中优先降解，而反式-(+)-(1S,2S)-联苯三唑醇在生菜中优先降解。对于非对映异构体，顺式联苯三唑醇在受试蔬菜中优先降解。消旋联苯三唑醇的降解半衰期如下：小白菜（0.57 - 0.74天）＜白菜（0.87 - 1.07天）＜芹菜（1.32 - 1.63天）＜生菜（1.75 - 2.37天）＜土壤（22.5 - 24.7天）。最后，生菜（0.0128 mg/kg）和芹菜（0.0289 mg/kg）中消旋联苯三唑醇的最终残留浓度高于最大残留限量（MRL，0.01 mg/kg），应引起关注。膳食风险评估结果表明，受试蔬菜中消旋联苯三唑醇的慢性膳食风险和急性膳食风险均可忽略不计。
