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意大利、荷兰和比利时青少年急性酒精中毒情况:一项跨国医院病历对比研究。

Acute alcohol intoxication among adolescents in Italy, the Netherlands and Belgium: a cross-national hospital chart comparison study.

作者信息

van Roozendaal Hanna, Pigeaud Louise, Ferrari Allegra, de Veld Loes, Verhulst Stijn, Glazemakers Inge, De Dooy Jozef, Icardi Giancarlo, Orsi Andrea, Van Hal Guido, van der Lely Nico

机构信息

Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium

Department of Paediatrics, Reinier de Graaf Hospital, Delft, Zuid-Holland, Netherlands.

出版信息

BMJ Paediatr Open. 2025 Mar 28;9(1):e003241. doi: 10.1136/bmjpo-2024-003241.

Abstract

BACKGROUND

Excessive drinking among adolescents in Western Europe is prevalent, posing significant health risks and societal costs. Comprehensive data on adolescent drinking patterns is crucial for developing effective prevention strategies. Data on alcohol intoxication among adolescents provide valuable insights in this context.

METHODS

To gain insight into the demographic and clinical characteristics of acute alcohol intoxication (AAI) across European countries, we analysed emergency department data on AAI among adolescents (aged 14-17) from 2015 to 2023 in three urban regions: Genoa (Italy), Delft (the Netherlands) and Antwerp (Belgium).

RESULTS

Out of 1826 admissions, Belgium had the highest median annual admission rate (51 per 10 000 adolescents), followed by the Netherlands (49 per 10 000) and Italy (37 per 10 000). The median age of patients was 16 years across all countries. Sex was equally distributed among Dutch patients; however, in Italy (not statistically significant, 55.6%) and Belgium (statistically significant, 56.8%), more males were admitted. The median blood alcohol concentration (BAC) was higher in the Netherlands (2.00 g/L) compared with Italy and Belgium (1.84 g/L and 1.97 g/L, respectively). This difference remained statistically significant after adjusting for confounders in a multiple linear regression model on BAC. Finally, the proportion of patients with combined drug use (10.4% of the total population) was similar across the three countries.

CONCLUSIONS

This is the first international study to consolidate data on AAI in minors from multiple countries, emphasising the need for a unified European database on AAI in adolescents to enhance prevention efforts.

摘要

背景

西欧青少年过度饮酒现象普遍,带来了重大的健康风险和社会成本。全面了解青少年饮酒模式的数据对于制定有效的预防策略至关重要。在此背景下,青少年酒精中毒数据提供了有价值的见解。

方法

为了深入了解欧洲各国急性酒精中毒(AAI)的人口统计学和临床特征,我们分析了2015年至2023年期间来自三个城市地区(意大利热那亚、荷兰代尔夫特和比利时安特卫普)14至17岁青少年AAI的急诊科数据。

结果

在1826例入院病例中,比利时的年入院率中位数最高(每10000名青少年中有51例),其次是荷兰(每10000名中有49例)和意大利(每10000名中有37例)。所有国家患者的年龄中位数均为16岁。荷兰患者中性别分布均匀;然而,在意大利(无统计学意义,55.6%)和比利时(有统计学意义,56.8%),入院的男性更多。与意大利和比利时(分别为1.84 g/L和1.97 g/L)相比,荷兰的血液酒精浓度(BAC)中位数更高(2.00 g/L)。在对BAC的多元线性回归模型中调整混杂因素后,这种差异仍然具有统计学意义。最后,三个国家联合使用药物的患者比例(占总人口的10.4%)相似。

结论

这是第一项整合多个国家未成年人AAI数据的国际研究,强调需要建立一个统一的欧洲青少年AAI数据库,以加强预防工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef92/11956305/f4a07b6af959/bmjpo-9-1-g001.jpg

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