Anzai Isao, Lawlor Matthew, Hahn Rebecca, Takayama Hiroo, Kodali Susheel, George Isaac
Division of Cardiac, Thoracic, and Vascular Surgery, Department of Surgery, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Division of Cardiology, Department of Medicine, New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
JACC Case Rep. 2025 Mar 19;30(6 Pt 2):102939. doi: 10.1016/j.jaccas.2024.102939. Epub 2025 Jan 8.
Transcatheter aortic valve replacement (TAVR) is rarely performed for pure aortic insufficiency. When aortic insufficiency occurs in the context of a prior valve-sparing aortic root replacement (VSARR), the anatomic complexity of performing TAVR is significantly increased. We report a case of successful TAVR deployment in a patient with severe aortic insufficiency soon after VSARR. TAVR deployment in a prior VSARR graft relies on positioning the valve between the running sinus suture line superiorly and in this case CorKnots inferiorly using an oversized balloon-expandable valve to limit paravalvular leak. This was successfully performed with no residual regurgitation. Nonoperative management using TAVR for high-risk surgical candidates can be safely performed for aortic insufficiency after failed VSARR in the acute setting. Proper sizing, valve selection, and positioning are of utmost importance in this setting although the presence of CorKnots used during VSARR may aid in optimal positioning.
经导管主动脉瓣置换术(TAVR)很少用于单纯主动脉瓣关闭不全。当在先前保留瓣膜的主动脉根部置换术(VSARR)的情况下发生主动脉瓣关闭不全时,进行TAVR的解剖复杂性会显著增加。我们报告了1例在VSARR后不久成功为重度主动脉瓣关闭不全患者进行TAVR植入的病例。在先前的VSARR移植物中进行TAVR植入依赖于将瓣膜置于上方的窦连续缝合线与下方(在本病例中为CorKnots)之间,使用超大号球囊扩张瓣膜来限制瓣周漏。此操作成功完成,无残余反流。对于急性情况下VSARR失败后的主动脉瓣关闭不全,使用TAVR对高风险手术候选者进行非手术治疗可安全实施。在这种情况下,合适的尺寸选择、瓣膜选择和定位至关重要,尽管VSARR期间使用的CorKnots可能有助于实现最佳定位。