Aloia J F, Yeh J K
Bone. 1985;6(2):73-7. doi: 10.1016/8756-3282(85)90310-2.
Intestinal active and passive transport of phosphate (Pi) was studied in hypophysectomized (HX) and intact rats using the in situ intestinal loop technique. Hypophysectomy resulted in a significant reduction of total Pi absorption under active transport conditions. However, when transport data were expressed on the basis of mucosal mass, the reduction was not apparent. Under passive transport conditions, net Pi absorption was lower in the HX rats even after correction for the decrease of mucosal mass. Administration of bovine growth hormone (bGH) did not change the intestinal Pi absorption in the HX rats. These results indicate that a decrease in mucosal mass following hypophysectomy is one of the factors that causes a decrease of intestinal Pi absorption.
采用原位肠袢技术，研究了垂体切除（HX）大鼠和完整大鼠肠道对磷酸盐（Pi）的主动转运和被动转运。垂体切除导致在主动转运条件下总Pi吸收显著降低。然而，当根据黏膜质量来表示转运数据时，这种降低并不明显。在被动转运条件下，即使校正了黏膜质量的减少，HX大鼠的净Pi吸收仍较低。给予牛生长激素（bGH）并未改变HX大鼠的肠道Pi吸收。这些结果表明，垂体切除后黏膜质量的减少是导致肠道Pi吸收降低的因素之一。
