Gibb D M, Arulkumaran S, Ratnam S S
Br J Obstet Gynaecol. 1985 Jul;92(7):688-92. doi: 10.1111/j.1471-0528.1985.tb01449.x.
Equipment has become available for the automatic infusion of oxytocin in a closed loop system for the induction of labour. This system was compared with manual administration of oxytocin by peristaltic infusion pump, the dosage being based on data derived from an intrauterine catheter or by clinical assessment of uterine activity. A total of 121 patients classified according to parity and cervical score were allocated to an automatic infusion system (AIS) or a peristaltic infusion pump system. Patient characteristics were similar in both groups. Labour was significantly longer in those induced by automatic infusion system particularly in nulliparae and patients with poor cervical scores. In 53.3% of the nulliparae with poor cervical scores the automatic infusion system proved inadequate to effect vaginal delivery. Neonatal outcome was similar in both groups. Automatic infusion of oxytocin by the present system increased the length of induced labour and had no statistically significant effect on neonatal outcome, conferring no advantage over a more traditional method of oxytocin administration.
现已具备在闭环系统中自动输注催产素以引产的设备。该系统与通过蠕动式输液泵手动输注催产素进行了比较，剂量基于从子宫内导管获得的数据或通过子宫活动的临床评估来确定。根据产次和宫颈评分分类的121例患者被分配到自动输注系统（AIS）或蠕动式输液泵系统。两组患者的特征相似。自动输注系统引产的患者产程明显更长，尤其是初产妇和宫颈评分差的患者。在宫颈评分差的初产妇中，53.3%的患者自动输注系统不足以实现阴道分娩。两组的新生儿结局相似。本系统自动输注催产素增加了引产的产程，对新生儿结局无统计学显著影响，与更传统的催产素给药方法相比没有优势。
