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肉毒杆菌毒素注射后主动脉-食管瘘

Aorto‑esophageal Fistula following Botox Injection.

作者信息

Saliba Thomas, Tack Denis

机构信息

Centre hospitalier universitaire vaudois (CHUV), Lausanne, Switzerland.

Hopital D'Ath (EpiCURA), Ath, Belgium.

出版信息

J Belg Soc Radiol. 2025 Mar 25;109(1):14. doi: 10.5334/jbsr.3868. eCollection 2025.

DOI:10.5334/jbsr.3868
PMID:40161364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11951977/
Abstract

Aorto‑esophageal fistulas (AEF) are rare, often fatal connections between the thoracic aorta and esophagus, arising from aortic disease, esophageal conditions, or iatrogenic causes. A 76‑year‑old woman, treated for esophageal nutcracker syndrome with endoscopic injection of botox, developed chest pain and esophageal hemorrhage. Computed tomography (CT) confirmed an AEF from an aortic pseudoaneurysm. She succumbed to circulatory collapse before treatment. Endoscopic botox injections are a rare cause of AEF. The diagnosis relies on imaging and endoscopy, with surgery often required. Aorto‑esophageal fistulas are rare, life‑threatening complications, particularly after iatrogenic procedures. Early diagnosis is crucial, but prognosis remains poor.

摘要

主动脉-食管瘘(AEF)是一种罕见的、常致命的胸主动脉与食管之间的连接,由主动脉疾病、食管疾病或医源性原因引起。一名76岁女性因内镜下注射肉毒杆菌毒素治疗食管胡桃夹综合征,出现胸痛和食管出血。计算机断层扫描(CT)证实为主动脉假性动脉瘤导致的主动脉-食管瘘。她在治疗前死于循环衰竭。内镜下注射肉毒杆菌毒素是主动脉-食管瘘的罕见病因。诊断依靠影像学和内镜检查,通常需要手术治疗。主动脉-食管瘘是罕见的、危及生命的并发症,尤其是在医源性操作之后。早期诊断至关重要,但预后仍然很差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/85469612db8d/jbsr-109-1-3868-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/ade88be06bf3/jbsr-109-1-3868-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/11c62dde6e96/jbsr-109-1-3868-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/85469612db8d/jbsr-109-1-3868-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/ade88be06bf3/jbsr-109-1-3868-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/11c62dde6e96/jbsr-109-1-3868-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/11951977/85469612db8d/jbsr-109-1-3868-g3.jpg

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本文引用的文献

1
A successful endovascular aortic repair of aortoesophageal fistula following esophagectomy: a case report and literature review.食管切除术后医源性主动脉-食管瘘的血管内修复成功:病例报告及文献复习。
J Cardiothorac Surg. 2024 Feb 7;19(1):70. doi: 10.1186/s13019-024-02540-1.
2
Case report: Aortoesophageal fistula-an extremely rare but life-threatening cardiovascular cause of hematemesis.病例报告:主动脉食管瘘——一种极为罕见但危及生命的咯血心血管病因。
Front Cardiovasc Med. 2023 Apr 20;10:1123305. doi: 10.3389/fcvm.2023.1123305. eCollection 2023.
3
Aortic Fistulas: Pathophysiologic Features, Imaging Findings, and Diagnostic Pitfalls.
主动脉瘘:病理生理特征、影像学表现及诊断陷阱。
Radiographics. 2021 Sep-Oct;41(5):1335-1351. doi: 10.1148/rg.2021210004. Epub 2021 Jul 30.
4
Mediastinitis, pseudo-aneurysm formation, aortic bleed, and death from endoscopic botulinum toxin injection.纵隔炎、假性动脉瘤形成、主动脉出血以及内镜下肉毒杆菌毒素注射导致的死亡。
Endoscopy. 2016;48 Suppl 1:E186-7. doi: 10.1055/s-0042-107074. Epub 2016 May 23.
5
Esophageal perforation, inflammatory mediastinitis and pseudoaneurysm of the thoracic aorta as potential complications of botulinum toxin injection for achalasia.食管穿孔、纵隔炎和胸主动脉假性动脉瘤是贲门失弛缓症注射肉毒毒素的潜在并发症。
Dig Endosc. 2015 Jul;27(5):618-21. doi: 10.1111/den.12392. Epub 2014 Dec 1.
6
Aortic bypass in the management of aortoesophageal fistula.主动脉旁路术在主动脉食管瘘治疗中的应用
Ann Thorac Surg. 1969 Mar;7(3):235-7. doi: 10.1016/s0003-4975(10)66178-4.