Shamoon Richard, Elhassan Osman, Al-Emadi Lujain, Zabara Abdulwahab, Petkar Mahir A, Sayed Sarah, Mohammad Osama H
Department of Internal Medicine, Hazm Mebaireek General Hospital, Street 33, Industrial Area, Al-Rayyan, Doha, Qatar.
Department of Medical Education, Hamad Medical Corporation (HMC), C-Ring Road, Hamad Medical City, Doha, Qatar.
Oxf Med Case Reports. 2025 Mar 28;2025(4):omaf011. doi: 10.1093/omcr/omaf011. eCollection 2025 Apr.
A 46-year-old male with no comorbidities was referred to our hospital because of jaundice and elevated LFT markers. After further investigations, he underwent magnetic resonance cholangiopancreatography (MRCP), which revealed a hypo-enhancing periampullary mass measuring 15 mm in size causing common bile duct (CBD) dilatation of 12 mm in cross diameter with intrahepatic biliary obstruction, which explained the patient's symptoms. Side-view endoscopy was performed to obtain a specimen of the mass. Further histopathological workup revealed poorly differentiated neuroendocrine carcinoma (NEC). A multidisciplinary team (MDT) was conducted, and the patient was planned to undergo positron emission tomography-computed tomography (PET-CT) scan to investigate any further organ metastasis. Unfortunately, the patient missed his upcoming appointments and was lost to follow-up. Nevertheless, more research is needed to understand pathogenesis and the best course of management for small periampullary NETs.
一名无合并症的46岁男性因黄疸和肝功能检查指标升高被转诊至我院。进一步检查后，他接受了磁共振胰胆管造影（MRCP），结果显示一个大小为15毫米的壶腹周围低强化肿块，导致胆总管（CBD）横径扩张12毫米，并伴有肝内胆管梗阻，这解释了患者的症状。进行了侧视内镜检查以获取肿块标本。进一步的组织病理学检查显示为低分化神经内分泌癌（NEC）。开展了多学科团队（MDT）讨论，并计划让患者接受正电子发射断层扫描-计算机断层扫描（PET-CT）以检查是否有其他器官转移。不幸的是，患者错过了后续预约，失访了。尽管如此，仍需要更多研究来了解小壶腹周围神经内分泌肿瘤（NETs）的发病机制和最佳治疗方案。
