[Experimental study of the antimutagenic properties of 5-methylresorcinol].
作者信息
Pashin Iu V, Bakhitova L M, Bentkhen T I
出版信息
Biull Eksp Biol Med. 1985 Jul;100(7):63-5.
PMID:4016243
Abstract
A study was made of the effect of 5-methylresorcinol (5-MR) on mutagenic activity of benzo(a)pyrene (BP) and of the action of gamma-radiation in in-vitro and in-vivo systems. The induction of direct gene mutations in Chinese hamster cells V-79 and micronuclei in mouse bone marrow reticulocytes was efficiently suppressed by 5-MR treatment. The antimutagenic activity of 5-MR can be explained by inhibition of free-radical processes.
摘要
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