[Influence of anticarcinogenic agents on the transplacental carcinogenic effect of N-nitroso-N-ethylurea].
作者信息
Bespalov V G, Aleksandrov V A
出版信息
Biull Eksp Biol Med. 1985 Jul;100(7):73-6.
PMID:4016244
Abstract
Experiments on rats were made to study the action of 7 anticarcinogenic substances administered postnatally for a long time (sodium selenite, retinol acetate, phenformin, amber acid, low-molecular polypeptide factors of the thymus, pineal gland, and bone marrow) on the transplacental carcinogenic effect of N-ethyl-N-nitrosourea (ENU) The polypeptide factors of the thymus and pineal gland and phenformin inhibited the development of nervous system and renal tumors induced transplacentally by ENU. The rest of the substances did not influence the transplacental carcinogenesis.
摘要
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