一种基于抗炎药物盐酸苄达明的用于检测铁离子的荧光探针。
A Fluorescent Probe Based on the Anti-Inflammatory Drug Benzydamine Hydrochloride for the Detection of Fe Ions.
作者信息
Wu Huiqin, Wang Zhimei, Li Bo, Chen Qing
机构信息
Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang, 550025, China.
School of Chemical Safety, North China Institute of Science and Technology, Langfang, 065201, China.
出版信息
J Fluoresc. 2025 Mar 31. doi: 10.1007/s10895-025-04284-0.
The detection of Fe by benzydamine hydrochloride (BNZ) and its mechanism were studied by UV, fluorescence, infrared, and H NMR spectroscopy. The results showed that BNZ could be used as a fluorescence probe to selectively identify Fe. Recognition results from coordination of Fe by BNZ that leads to fluorescence quenching by electron transfer. A 1:1 complex is formed between BNZ and Fe with a binding constant of 3.619 × 10 M. The fluorescence intensity of BNZ was linearly correlated with the concentration of Fe from 3.0 × 10 to 2.3 × 10 M, the detection limit was as low as 1.24 × 10 M, and the recovery rate of Fe detected in tap water was 96-98%, which could enable quantitative detection and monitoring of Fe in environmental systems, and the method is simple, accurate, low detection limit, and can detect Fe quickly, selectively, and sensitively.
通过紫外光谱、荧光光谱、红外光谱和核磁共振氢谱研究了盐酸苄达明（BNZ）对铁的检测及其机理。结果表明，BNZ可作为荧光探针选择性识别铁。铁与BNZ配位导致电子转移使荧光猝灭的识别结果。BNZ与铁形成1:1配合物，结合常数为3.619×10 M。BNZ的荧光强度与铁的浓度在3.0×10至2.3×10 M范围内呈线性相关，检测限低至1.24×10 M，自来水中铁的回收率为96 - 98%，可实现环境体系中铁的定量检测与监测，该方法简便、准确、检测限低，能快速、选择性且灵敏地检测铁。
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