Leong Benjamin J, Corbett James, Chen Darren B, Kirsh George, Leong Anthony K L, Wood Jil A, Diwan Ashish D, Wernecke Gregory C, Harris Ian A, MacDessi Samuel J
Sydney Knee Specialists, Sydney, Australia.
School of Clinical Medicine, UNSW Sydney, Sydney, Australia.
Bone Joint J. 2025 Apr 1;107-B(4):413-422. doi: 10.1302/0301-620X.107B4.BJJ-2024-0204.R3.
Previous research on knee kinematics has demonstrated that achieving a tibial joint line angle (TJLA) parallel to the floor in the single-leg stance phase of gait may restore native knee kinematics and optimize compartmental compressive loads in total knee arthroplasty (TKA). However, it is currently unclear which surgical alignment strategy best achieves this. Therefore, this study sought to determine whether kinematically aligned (KA) or mechanically aligned (MA) TKAs produce a TJLA closer to parallel.
A total of 95 patients were randomized to KA (n = 46) or MA (n = 49). Constitutional joint line obliquity (JLO) was measured from preoperative radiographs; TJLA was measured from postoperative radiographs. The primary outcome was the mean difference in TJLA between KA and MA in single-leg stance. Secondary outcomes included differences in TJLA between apex distal and neutral JLO knees, the proportion of patients with TJLA within approximately 2° of neutral, and changes in constitutional JLO between alignment groups.
In single-leg stance, the mean TJLA was closer to parallel with KA (-2.0° (SD 2.6°)) than MA (-4.5° (SD 1.9°); p < 0.001). Similar mean differences were observed in patients with apex distal JLO (KA -1.4° (SD 2.1°); MA -4.9° (SD 1.8°); p < 0.001) but not neutral JLO (KA -3.7° (SD 2.8°); MA -3.7° (SD 1.9°); p = 0.776). More patients had a TJLA within 2° of parallel with KA (n = 24; 52.2%) than MA (n = 4; 8.2%; p < 0.001), and KA resulted in significantly less change to constitutional JLO.
A TJLA parallel to the floor in single-leg stance is achieved more readily with KA than MA, but is dependent on constitutional JLO. A parallel TJLA during this phase of gait is more likely achieved when alignment is individualized to the patient's native anatomy.
以往关于膝关节运动学的研究表明,在步态的单腿站立阶段使胫股关节线角(TJLA)与地面平行,可能恢复膝关节的自然运动学,并优化全膝关节置换术(TKA)中的关节间压缩负荷。然而,目前尚不清楚哪种手术对线策略最能实现这一点。因此,本研究旨在确定运动学对线(KA)或机械对线(MA)的TKA是否能使TJLA更接近平行。
总共95例患者被随机分为KA组(n = 46)或MA组(n = 49)。术前X线片测量先天性关节线倾斜度(JLO);术后X线片测量TJLA。主要结局是单腿站立时KA组和MA组TJLA的平均差异。次要结局包括顶点远端JLO膝关节与中立JLO膝关节之间TJLA的差异、TJLA在中立值约2°范围内的患者比例,以及对线组之间先天性JLO的变化。
在单腿站立时,KA组的平均TJLA(-2.0°(标准差2.6°))比MA组(-4.5°(标准差1.9°))更接近平行(p < 0.001)。顶点远端JLO的患者也观察到类似的平均差异(KA组-1.4°(标准差2.1°);MA组-4.9°(标准差1.8°);p < 0.001),但中立JLO的患者未观察到(KA组-3.7°(标准差2.8°);MA组-3.7°(标准差1.9°);p = 0.776)。TJLA在平行值2°范围内的KA组患者(n = 24;52.2%)多于MA组(n = 4;8.2%;p < 0.001),并且KA导致先天性JLO的变化明显更小。
与MA相比,KA更容易在单腿站立时使TJLA与地面平行,但这取决于先天性JLO。当根据患者的自然解剖结构进行个体化对线时,在步态的这一阶段更有可能实现平行的TJLA。