Cookson J C, Silverstone T, Williams S, Besser G M
Br J Psychiatry. 1985 May;146:498-502. doi: 10.1192/bjp.146.5.498.
Plasma cortisol levels were elevated in a large proportion of samples from manic patients. Although a correlation was found between clinical ratings of the severity of mania and the degree of elevation of daytime cortisol levels, some patients with low clinical ratings had elevated cortisol levels. During treatment with haloperidol, cortisol levels returned to normal earlier that the clinical state. The underlying mechanisms are discussed.
在很大一部分躁狂症患者的样本中，血浆皮质醇水平升高。尽管发现躁狂严重程度的临床评分与日间皮质醇水平升高程度之间存在相关性，但一些临床评分较低的患者皮质醇水平也升高。在使用氟哌啶醇治疗期间，皮质醇水平比临床状态更早恢复正常。文中讨论了潜在机制。
