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本文引用的文献

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3R centres contributions to change animal experimentation : A field report from Charité 3, the 3R centre of a medical faculty.3R 中心对改变动物实验的贡献：来自 Charité 3 的现场报告，Charité 3 是一所医学系的 3R 中心。
EMBO Rep. 2024 Oct;25(10):4105-4109. doi: 10.1038/s44319-024-00262-y. Epub 2024 Sep 13.
2
Negative equity - the value of reporting negative results.负资产——报告负结果的价值。
Dis Model Mech. 2024 Aug 1;17(8). doi: 10.1242/dmm.050937. Epub 2024 Aug 30.
3
3R centers tap into the human mindset to bolster replacement, reduction and refinement uptake.3R中心利用人类思维模式来促进替代、减少和优化的应用。
Lab Anim (NY). 2024 Jul;53(7):166-169. doi: 10.1038/s41684-024-01396-1.
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Optimizing environmental enrichment for Sprague Dawley rats: Exemplary insights into the liver proteome.优化 Sprague Dawley 大鼠的环境丰容：对肝蛋白质组学的典型见解。
PLoS One. 2024 Apr 18;19(4):e0297497. doi: 10.1371/journal.pone.0297497. eCollection 2024.
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Using refined methods to pick up mice: A survey benchmarking prevalence & beliefs about tunnel and cup handling.用改良的方法挑选小鼠：一项关于隧道和杯子处理的流行程度和观念的调查基准。
PLoS One. 2023 Sep 7;18(9):e0288010. doi: 10.1371/journal.pone.0288010. eCollection 2023.
6
Environmental Enrichment for Rats and Mice Housed in Laboratories: A Metareview.实验室饲养大鼠和小鼠的环境丰富化：一项元综述。
Animals (Basel). 2022 Feb 9;12(4):414. doi: 10.3390/ani12040414.
7
3Rs missing: animal research without scientific value is unethical.“3Rs”缺失：没有科学价值的动物研究是不道德的。
BMJ Open Sci. 2019 Jul 4;3(1). doi: 10.1136/bmjos-2018-000048. eCollection 2019.
8
Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis.常规实验室饲养增加了研究啮齿动物的发病率和死亡率：一项荟萃分析的结果。
BMC Biol. 2022 Jan 13;20(1):15. doi: 10.1186/s12915-021-01184-0.
9
Epidemiology and reporting characteristics of preclinical systematic reviews.临床前系统评价的流行病学和报告特征。
PLoS Biol. 2021 May 5;19(5):e3001177. doi: 10.1371/journal.pbio.3001177. eCollection 2021 May.
10
The environmental enrichment model revisited: A translatable paradigm to study the stress of our modern lifestyle.重新审视环境丰富模型：一种可转化的范例，用于研究我们现代生活方式的压力。
Eur J Neurosci. 2022 May;55(9-10):2359-2392. doi: 10.1111/ejn.15160. Epub 2021 Mar 15.

不可名状之物：提升研究中动物福利的事实、情感及应对策略

What must not be named : Facts, emotions and coping strategies to enhance animal welfare in research.

作者信息

Riesner Katarina, Hammerich Linda, Jahn Denise, Ellinghaus Agnes, Polenz Dietrich, Grohmann Lisa, Unger Juliane K

机构信息

Taskforce Refinement, Charité - Univeristätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universitätsmedizin Berlin, Berlin, Germany.

Department of Hematology, Oncology and Tumorimmunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

出版信息

EMBO Rep. 2025 Apr;26(8):1929-1934. doi: 10.1038/s44319-025-00429-1. Epub 2025 Mar 31.

DOI:10.1038/s44319-025-00429-1
PMID:40164901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12019234/
Abstract

Scientists working with animals must maintain a delicate balance between conducting high-quality science and legal and ethical responsibilities. It is time to openly discuss their workload and emotional burden to improve both animal welfare and scientific quality in biomedical research. [Image: see text]

摘要

从事动物研究的科学家必须在开展高质量科研工作与履行法律及道德责任之间保持微妙的平衡。现在是时候公开讨论他们的工作量和情感负担了，以便在生物医学研究中提高动物福利和科研质量。 [图片：见正文]