Scorza Fulvio A, Attis Cintia, Wuo-Silva Raphael, Ciconelli Rozana M, Chaddad-Neto Feres
Disciplina de Neurociência, Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brasil.
Unidade de Neurocirurgia, Hospital A Beneficência de São Paulo, São Paulo, Brasil.
HERD. 2025 Mar 31:19375867251330819. doi: 10.1177/19375867251330819.
The therapeutic effects of biophilia have garnered increasing attention in hospital settings, as recent research highlights its impact on psychological metrics such as anxiety, depression, pain, and patient satisfaction. In their 2024 study, Guidolin et al. present compelling data supporting the role of nature exposure in improving patient outcomes. Building on this, we explore a possible link between biophilia and brain plasticity. The human brain's neuroplasticity, particularly adult hippocampal neurogenesis, responds dynamically to environmental stimuli, including enriched environments. Studies suggest that biophilic design, by integrating natural elements to built spaces, can positively influence brain function and mental health. Furthermore, interactions with nature may upregulate neurogenesis in the hippocampus, a region critical for memory and emotional regulation. These findings support the integration of biophilia as a potential non-pharmacological approach to enhance cognitive and psychological health. We propose that future architectural projects should leverage biophilic design to harness these therapeutic benefits, particularly in healthcare environments, to promote well-being and brain function.
亲生物性的治疗效果在医院环境中受到了越来越多的关注，因为最近的研究突出了其对焦虑、抑郁、疼痛和患者满意度等心理指标的影响。在2024年的研究中，吉多林等人展示了令人信服的数据，支持接触自然对改善患者预后的作用。在此基础上，我们探讨亲生物性与大脑可塑性之间的可能联系。人类大脑的神经可塑性，尤其是成人海马神经发生，会对包括丰富环境在内的环境刺激做出动态反应。研究表明，通过将自然元素融入建筑空间的亲生物设计，可以对大脑功能和心理健康产生积极影响。此外，与自然的互动可能会上调海马体中的神经发生，海马体是对记忆和情绪调节至关重要的区域。这些发现支持将亲生物性作为一种潜在的非药物方法来增强认知和心理健康。我们建议未来的建筑项目应利用亲生物设计来利用这些治疗益处，特别是在医疗环境中，以促进幸福感和大脑功能。
