Sturm Malin C K, Abazid Alexander, Stope Matthias B
Department of Gynecology and Gynecological Oncology, University Hospital Bonn, D-53127 Bonn, Germany.
Department of General, Visceral and Thorax Surgery, Bundeswehr Hospital Berlin, D-10115 Berlin, Germany.
Exp Ther Med. 2025 Mar 17;29(5):97. doi: 10.3892/etm.2025.12847. eCollection 2025 May.
Tissue adhesion after surgical procedures is a common postoperative complication that affects a significant number of patients across all surgical disciplines. In pelvic surgical procedures, second-look surgeries have revealed adhesions in more than half of all patients weeks to several months after surgery. Adhesions can be asymptomatic, but they can also cause a wide range of complications, such as severe pain, nausea, vomiting, constipation, ileus and reproductive dysfunction. Undetected adhesions that lead to problems in subsequent surgical interventions are also of high clinical importance. Lysis of these adhesions before the actual surgery leads to loss of time and possible additional complications, such as trocar injuries in laparoscopies or inadvertent enterotomies during adhesiolysis, during the originally planned intervention. The health care associated with adhesion-related problems are significant. Because of the widely varying manifestations of symptoms, the already concerning figure of patients with significant adhesions is likely to increase. Outpatient healthcare expenditures are further increased because of undetected adhesions. Adhesions therefore represent a major surgical and health economic problem; however, yet there are currently few options for prophylaxis and treatment.
外科手术后的组织粘连是一种常见的术后并发症，影响着所有外科领域的大量患者。在盆腔外科手术中，二次探查手术显示，超过半数的患者在术后数周乃至数月出现粘连。粘连可能没有症状，但也会引发一系列并发症，如剧痛、恶心、呕吐、便秘、肠梗阻和生殖功能障碍。未被发现的粘连在后续手术干预中导致问题，其临床重要性也很高。在实际手术前松解这些粘连会导致时间浪费以及可能出现额外的并发症，比如腹腔镜手术中的套管针损伤，或者在最初计划的粘连松解术中意外的肠切开术。与粘连相关问题的医疗保健费用很高。由于症状表现差异很大，粘连严重患者的数量本已令人担忧，而且很可能还会增加。由于未被发现的粘连，门诊医疗费用进一步增加。因此，粘连是一个重大的外科和健康经济问题；然而，目前预防和治疗的选择却很少。
