van Goor H
Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Colorectal Dis. 2007 Oct;9 Suppl 2:25-34. doi: 10.1111/j.1463-1318.2007.01358.x.
Consequences and complications of postsurgical intra-abdominal adhesion formation not including small bowel obstruction and secondary infertility are substantial but are under-exposed in the literature. Inadvertent enterotomy during reopening of the abdomen or subsequent adhesion dissection is a feared complication of surgery after previous laparotomy. The incidence can be as high as 20% in open surgery and between 1% and 100% in laparoscopy depending on the underlying disease. Delayed postoperative detection of enterotomy is a particular feature of laparoscopy associated with significant morbidity and mortality. Adhesions to the ventral abdominal wall are responsible for the majority of trocar injuries. Both trocar injuries and inadvertent enterotomies result in conversion from laparoscopy to laparotomy in almost 100% of cases. There is a paucity of data on other organ injury, such as liver laceration or bladder perforation. Dissecting adhesions before executing the planned operation takes on average 20 min, being one-fifth of the total operating time in patients having had previous open colorectal surgery. There is some evidence that postoperative morbidity and mortality of patients who need adhesiolysis is higher than that of patients with a virgin abdomen. The necessity to dissect adhesions is associated with increased hospital stay. Postsurgical adhesions are considered a main reason for conversion from laparoscopy to laparotomy in many types of procedures including laparoscopic colonic resection. Adhesion formation is part of the innate peritoneal defence mechanism in peritonitis. Abscess formation and bleeding, organ injury and fistula formation at 'on demand' relaparotomies are well-known complications after surgery for intra-abdominal sepsis associated with fibrinous adhesions. The clinical magnitude hereof is poorly researched. Postsurgical adhesions may cause pain as evidenced by pain mapping clinical experiments. Filmy adhesions between movable organs and the peritoneum appear to be worse in terms of generating pain. The high caseload of gynaecological and some colorectal practices suggest an enormous impact of adhesion-related chronic abdominal and pelvic pain on patient's wellbeing and socio-economic costs. The significant risk of inadvertent enterotomy, conversion to laparotomy and trocar injury, and the associated postoperative morbidity and mortality and increased length of hospital stay warrant routine informed consent of adhesiolysis related complications in patients scheduled for abdominal or pelvic reoperation.
术后腹腔内粘连形成的后果及并发症(不包括小肠梗阻和继发性不孕)较为严重,但在文献中报道较少。在再次开腹或后续粘连松解术中意外肠切开是既往剖腹手术后令人担忧的并发症。开放手术中发生率高达20%,腹腔镜手术中发生率在1%至100%之间,具体取决于基础疾病。腹腔镜术后肠切开延迟发现是其一个特殊特征,会导致显著的发病率和死亡率。与腹前壁的粘连是大多数套管针损伤的原因。套管针损伤和意外肠切开几乎在100%的病例中都会导致从腹腔镜手术转为开腹手术。关于其他器官损伤,如肝撕裂或膀胱穿孔的数据较少。在执行计划手术前松解粘连平均需要20分钟,占既往接受过开放性结直肠手术患者总手术时间的五分之一。有证据表明需要进行粘连松解术的患者术后发病率和死亡率高于未开过腹的患者。粘连松解的必要性与住院时间延长有关。在包括腹腔镜结肠切除术在内的许多手术中,术后粘连被认为是从腹腔镜手术转为开腹手术的主要原因。粘连形成是腹膜炎中固有腹膜防御机制的一部分。在因腹腔内脓毒症伴纤维蛋白性粘连进行“按需”再次剖腹手术时脓肿形成、出血、器官损伤和瘘管形成是众所周知的并发症。对此临床严重程度的研究较少。术后粘连可能会引起疼痛,疼痛定位临床实验已证实这一点。可移动器官与腹膜之间的薄膜状粘连似乎在产生疼痛方面更严重。妇科和一些结直肠科的高病例数表明,粘连相关的慢性腹部和盆腔疼痛对患者的健康和社会经济成本有巨大影响。意外肠切开、转为开腹手术和套管针损伤的重大风险,以及相关的术后发病率和死亡率及住院时间延长,使得对计划进行腹部或盆腔再次手术的患者,常规告知粘连松解相关并发症并取得知情同意成为必要。