Piccolo Domenico, Pieri Laura, Fusco Irene, Zingoni Tiziano, Conforti Claudio, Tramontozzi Sabrina
Novea Skin Center-Dermo Aesthetic Laser Centers, Pescara and L'Aquila, Avezzano, Italy.
Department of Clinical Research and Practice, El.En. Group, Calenzano 50041, Italy.
Case Rep Med. 2025 Mar 23;2025:9034642. doi: 10.1155/carm/9034642. eCollection 2025.
Classic Kaposi's sarcoma (CKS) is distinguished by nodules and clustered papules over the extremities with persistent edema. This report examine the results of neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser for the treatment of numerous nodular symptomatic nodules in CKS patients' lower extremities that are ineligible for systemic therapy. Each lesion received two sessions Nd:YAG laser treatment performed at 1-month intervals. Pretreatment and follow-up visit (after 3 months) were accompanied by clinical photographs and improvement was assessed by a skilled medical professional by comparing before- and after-treatment photos as well as by looking at patients directly. Videodermoscopy was performed on all lesions. : Just one session with long-pulsed Nd:YAG laser proved to be successful, with the immediate coagulation of the lesions and the disappearance of most of them. Every single lesion healed in two to 4 weeks. Only one lesion, the largest one, presented a water blister after treatment, which resolved within a few days. At 2 months follow up, the patient reported total pain relief and full recovery after the symptomatic nodules vanished. Nd:YAG laser could represent a rapid and advantageous therapeutic approach for both early- and advanced-stage CKS patients.
经典型卡波西肉瘤（CKS）的特征是四肢出现结节和成群的丘疹，并伴有持续性水肿。本报告探讨了掺钕钇铝石榴石（Nd:YAG）激光治疗CKS患者下肢大量有症状的结节性病变的效果，这些病变不适合进行全身治疗。每个病变接受间隔1个月进行的两个疗程的Nd:YAG激光治疗。治疗前和随访（3个月后）均伴有临床照片，由专业医生通过比较治疗前后照片以及直接观察患者来评估改善情况。对所有病变进行了视频皮肤镜检查。结果显示，仅一个疗程的长脉冲Nd:YAG激光治疗就取得了成功，病变立即凝固，大多数病变消失。每个病变在2至4周内愈合。仅最大的一个病变在治疗后出现了水疱，几天后消退。在2个月的随访中，患者报告症状性结节消失后疼痛完全缓解且已完全康复。Nd:YAG激光可能是早期和晚期CKS患者一种快速且有效的治疗方法。
