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谈疾病改善抗风湿药物的使用障碍:类风湿关节炎患者常规临床诊疗录音的内容分析

Talking About Barriers to Disease-Modifying Anti-Rheumatic Drugs: Content Analysis of Audio-Recorded Routine Clinical Visits of Patients with Rheumatoid Arthritis.

作者信息

Voshaar Marieke J H, Van den Bemt Bart J F, van de Laar Mart A, van Dulmen Sandra, Vriezekolk Johanna E

机构信息

Radboud University Medical Center, Department of Pharmacy, Nijmegen, the Netherlands.

Sint Maartenskliniek, Department of Pharmacy, Nijmegen, the Netherlands.

出版信息

Patient Prefer Adherence. 2025 Mar 27;19:777-790. doi: 10.2147/PPA.S503083. eCollection 2025.

Abstract

PURPOSE

Effective healthcare professional-patient communication is essential for medication adherence. Conversations about patient's barriers to medication use, for example, could help to enhance adherence and consequently improve treatment outcomes. However, it is unclear whether and how barriers to medication use are discussed during routine rheumatology consultations. The aims of this study were to examine 1) the barriers and facilitators to medication use raised by patients during real-life rheumatology outpatient consultations, and whether the issue of medication (non)adherence was discussed (communication content); and 2) how rheumatologists responded to the barriers (communication process).

METHODS

A total of 134 audio-recordings of real-life outpatient rheumatology consultations were analysed. Barriers and facilitators for the current use of disease-modifying anti-rheumatic drugs were identified and categorized using a previously adapted Theoretical Domains Framework. The way rheumatologists responded to the barriers brought up by the patients was analysed using relevant parts of the Roter Interaction Analysis System.

RESULTS

In 58 of the 134 consultations, at least one barrier or facilitator to current medication use was brought up by the patient; in 31 out of 134 consultations, medication (non)adherence was addressed. Most facilitators were related to the quality of the needles, the use of an injection pen instead of a syringe, dose reduction because of low disease activity and timing of the medication. The majority of barriers were related to experiencing side effects and doubts about efficacy and resistance of (long-term use of) medication. Rheumatologists' responses to barriers related to disease-modifying anti-rheumatic drugs were mostly a combination of instrumental (counselling) and affective (agreement) communication.

CONCLUSION

Barriers to current disease-modifying anti-rheumatic drugs' use raised by patients and discussed during routine rheumatology consultations were primarily related to side effects and concerns about the efficacy and long-term use. Continuous attention of these barriers and tailored responses to patients' concerns are key to promote better adherence to treatment.

摘要

目的

有效的医护人员与患者之间的沟通对于药物依从性至关重要。例如,关于患者用药障碍的对话有助于提高依从性,从而改善治疗效果。然而,在常规风湿病会诊中是否以及如何讨论用药障碍尚不清楚。本研究的目的是检查:1)在现实生活中的风湿病门诊会诊期间患者提出的用药障碍和促进因素,以及是否讨论了药物(不)依从性问题(沟通内容);2)风湿病医生如何应对这些障碍(沟通过程)。

方法

对134次现实生活中的门诊风湿病会诊的音频记录进行了分析。使用先前改编的理论领域框架确定并分类了目前使用改善病情抗风湿药物的障碍和促进因素。使用罗特互动分析系统的相关部分分析了风湿病医生对患者提出的障碍的反应方式。

结果

在134次会诊中的58次中,患者至少提出了一个目前用药的障碍或促进因素;在134次会诊中的31次中,讨论了药物(不)依从性。大多数促进因素与针头质量、使用注射笔而非注射器、因疾病活动度低而减少剂量以及用药时间有关。大多数障碍与经历副作用以及对药物(长期使用)的疗效和耐药性的怀疑有关。风湿病医生对与改善病情抗风湿药物相关障碍的反应大多是工具性(咨询)和情感性(认同)沟通的结合。

结论

患者提出并在常规风湿病会诊中讨论的目前使用改善病情抗风湿药物的障碍主要与副作用以及对疗效和长期使用的担忧有关。持续关注这些障碍并针对患者的担忧做出针对性回应是促进更好治疗依从性的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4916/11956895/35b933121512/PPA-19-777-g0001.jpg

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