Department of Pharmacy, Sint Maartenskliniek, Nijmegen, The Netherlands.
Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands.
Br J Clin Pharmacol. 2021 Mar;87(3):1082-1088. doi: 10.1111/bcp.14467. Epub 2020 Jul 26.
Adherence to statins ranges from 32% to 79%. Patients' beliefs about medication are associated with adherence. There is lack of insight into the possible association between beliefs of healthcare practitioners (HCPs) about statins and patients' beliefs and adherence. This study aims to examine whether HCPs' beliefs about statins are associated with patients' beliefs and adherence about/to statins.
Cross-sectional study in 48 pharmacies and affiliated physicians' practices between 3 September 2014 and 20 March 2015. HCPs' (prescribers and pharmacy staff) and patients' beliefs about statins were assessed with the Beliefs about Medicine Questionnaire (BMQ) specific. Adherence to statins was assessed with the MARS-5 questionnaire. Multilevel regression analysis was performed to assess the association between HCPs' beliefs and patients' beliefs and adherence.
1504 patients (mean age 66.8 [s.d. ± 9.9] years, 46.5% female) and 734 HCPs (209 physicians, 118 pharmacists and 366 pharmacy technicians) participated in this study. Patients have higher BMQ necessity (16.9 [s.d. ± 4.3]) and BMQ concern (12.3 [s.d. ± 3.9]) scores than HCPs (15.0 [s.d. ± 3.0] and 11.5 [s.d. ± 2.9], P < 0.001). No associations were found between any of the HCPs' BMQ and patients' BMQ scores and adherence to statins. Patients' BMQ necessity, concern and necessity-concerns (NC)-differential scores were associated with patients' adherence (MARS-5) scores. B (95% CI) coefficients were 0.057 (0.035-0.079), -0.040 (-0.064 to -0.016) and.061 (0.043-0.079).
Patients have stronger beliefs about medication compared to HCPs. No associations were found between HCPs' BMQ scores on the one hand and patients' BMQ scores and adherence to statins on the other hand.
他汀类药物的依从率为 32%至 79%。患者对药物的信念与依从性有关。目前尚不清楚医疗保健从业者（HCP）对他汀类药物的信念与患者对他汀类药物的信念和依从性之间可能存在的关联。本研究旨在探讨 HCP 对他汀类药物的信念是否与患者对他汀类药物的信念和依从性有关。
2014 年 9 月 3 日至 2015 年 3 月 20 日期间，在 48 家药店及其附属医生诊所进行了横断面研究。采用专门的药物信念问卷（BMQ）评估 HCP（处方者和药剂师）和患者对他汀类药物的信念。采用 MARS-5 问卷评估他汀类药物的依从性。采用多水平回归分析评估 HCP 信念与患者信念和依从性之间的关系。
共有 1504 名患者（平均年龄 66.8 [s.d. ± 9.9] 岁，46.5%为女性）和 734 名 HCP（209 名医生、118 名药剂师和 366 名药剂技术员）参与了这项研究。患者的 BMQ 必要性（16.9 [s.d. ± 4.3]）和 BMQ 关注（12.3 [s.d. ± 3.9]）评分高于 HCP（15.0 [s.d. ± 3.0] 和 11.5 [s.d. ± 2.9]，P < 0.001）。HCP 的任何 BMQ 与患者的 BMQ 评分和他汀类药物的依从性之间均无相关性。患者的 BMQ 必要性、关注和必要性-关注（NC）差异评分与患者的依从性（MARS-5）评分相关。B（95%CI）系数分别为 0.057（0.035-0.079）、-0.040（-0.064 至 -0.016）和 0.061（0.043-0.079）。
与 HCP 相比，患者对药物的信念更强。HCP 的 BMQ 评分与患者的 BMQ 评分和他汀类药物的依从性之间无相关性。
