Blake L, Jarvis C D, Mishkin M
Brain Res. 1977 Jan 21;120(2):209-20. doi: 10.1016/0006-8993(77)90901-5.
Ablation of inferior temporal (IT) cortex, particularly of the posterior region, produces severe impairment in pattern discrimination learning. The present study examined whether this impairment is associated with raised pattern discrimination thresholds. Groups of three monkeys each were given either anterior IT, posterior IT, or foveal striate lesions, or kept as controls. They were trained after surgery on a threshold task in which a 90 degrees white angle on a gray ground was the standard, and 15 angles ranging from 10 degrees through 88.5 degrees were the comparisons. As expected, monkeys with posterior IT lesions were the most severely impaired in learning the initial discrimination (90 degrees vs. 10 degrees). However, only the monkeys with foveal striate lesions showed significant impairment on the subsequent threshold determinations. The results indicate that raised pattern discrimination thresholds are not the cause of the pattern discrimination learning deficits produced by inferior temporal lesions. Data from additional visual discriminations presented after threshold testing was completed point, instead, to a loss of attention to stimulus features as the explanation for the learning deficit.
切除颞下（IT）皮质，尤其是后部区域，会导致模式辨别学习出现严重障碍。本研究探讨了这种障碍是否与模式辨别阈值升高有关。将每组三只猴子分别进行前颞下皮质、后颞下皮质或中央凹纹状皮质损伤，或作为对照。术后对它们进行一项阈值任务训练，其中以灰色背景上90度的白色角为标准，15个从10度到88.5度的角为比较对象。正如预期的那样，后颞下皮质损伤的猴子在学习初始辨别（90度对10度）时受损最严重。然而，只有中央凹纹状皮质损伤的猴子在随后的阈值测定中表现出显著损伤。结果表明，模式辨别阈值升高不是颞下损伤导致模式辨别学习缺陷的原因。相反，在阈值测试完成后进行的其他视觉辨别数据表明，对刺激特征的注意力丧失是学习缺陷的原因。
