Horel J A, Misantone L J
Science. 1976 Jul 23;193(4250):336-8. doi: 10.1126/science.819992.
An attempt was made to transect the white matter that connects the anterior temporal lobe with dorsal and medial brain areas. Eight monkeys were trained preoperatively on a visual discrimination and tested postoperatively for retention and relearning of the task. They were also tested for Klüver-Bucy symptoms. The two animals that had complete lesions were unable to relearn the visual discrimination. It is suggested that human medial temporal lesions may produce their effects on learning and retention by damage to temporal white matter rather than by destruction of hippocampus.
有人试图横断连接颞叶前部与脑背侧及内侧区域的白质。术前对八只猴子进行了视觉辨别训练，并在术后测试了该任务的记忆保持和重新学习情况。还对它们进行了克吕弗-布西症状测试。两只白质完全受损的动物无法重新学习视觉辨别任务。研究表明，人类颞叶内侧病变可能是通过损伤颞叶白质而非破坏海马体来对学习和记忆保持产生影响。
