Clark G B, Henry J M, McKeever P E
Cancer. 1985 Sep 1;56(5):1128-33. doi: 10.1002/1097-0142(19850901)56:5<1128::aid-cncr2820560529>3.0.co;2-j.
Cerebral pilocytic astrocytoma is a known intracranial tumor, but its biological characteristics are less well documented. The authors report 30 patients with cerebral pilocytic astrocytoma who were accessioned by the Armed Forces Institute of Pathology between 1970 and 1980. Histological appearance of the tumor was correlated with clinical characteristics. Mean age of onset was 22.15 years, mean preoperative duration of symptoms was 3.77 years, and mean postoperative survival was 5.91 years, with 20 of 23 (87%) known to ultimately survive surgery. These cases of cerebral pilocytic astrocytoma exhibited histologic characteristics consistent with that of a low-grade tumor. Although several of these tumors were of guarded prognosis due to location, degree of infiltration or cyst recurrence, they generally demonstrated a natural course of a relatively low-grade neoplasm.
大脑毛细胞型星形细胞瘤是一种已知的颅内肿瘤，但其生物学特性的文献记载较少。作者报告了1970年至1980年间美国武装部队病理研究所收录的30例大脑毛细胞型星形细胞瘤患者。肿瘤的组织学表现与临床特征相关。发病的平均年龄为22.15岁，术前症状持续的平均时间为3.77年，术后平均生存期为5.91年，23例中有20例（87%）最终存活下来。这些大脑毛细胞型星形细胞瘤病例表现出与低级别肿瘤一致的组织学特征。尽管其中一些肿瘤由于位置、浸润程度或囊肿复发而预后不佳，但它们总体上表现出相对低级别肿瘤的自然病程。
