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凯斯蒂发红量表:一种用于评估美容和临床皮肤病学中面部发红的新型工具的初步验证研究。

The Kesty Redness Scale: A Pilot Validation Study for a Novel Tool for Evaluating Facial Redness in Cosmetic and Clinical Dermatology.

作者信息

Kesty Chelsea E, Kesty Katarina R

机构信息

St. Petersburg Skin and Laser, St. Petersburg, Florida, USA.

Kesty AI, St. Petersburg, Florida, USA.

出版信息

J Cosmet Dermatol. 2025 Apr;24(4):e70039. doi: 10.1111/jocd.70039.

DOI:10.1111/jocd.70039
PMID:40167339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11960421/
Abstract

BACKGROUND

Facial redness is a common concern in dermatology, affecting patients with conditions such as rosacea, post-inflammatory erythema, and other vascular irregularities. Despite its prevalence, existing tools for quantifying facial redness are limited in their clinical utility and ease of use.

AIMS

To develop a high-performing redness scale.

METHODS

This study introduces the Kesty Redness Scale (KRS), outlines its development and validation process, and discusses its potential clinical applications.

RESULTS

The investigators rated the scale as useful and easy to use, and the majority stated they would use it in clinical practice to document patient characteristics. The results of the evaluation utilizing Gwet's AC2, Kendall's W, Spearman's ρ, Weighted Cohen's kappa, and Bland-Altman analysis -showcasing strong ordinal agreement, robust rank concordance, and negligible bias-demonstrate that this new rating system is both reliable and valid for measuring skin hyperpigmentation on a 0-3 scale.

CONCLUSIONS

The KRS is a reliable, easy-to-use tool that enhances the assessment of facial redness in dermatology. Its validation through expert evaluation and statistical analysis underscores its potential to improve clinical practice and research.

摘要

背景

面部发红是皮肤科常见问题,影响酒渣鼻、炎症后红斑及其他血管异常疾病的患者。尽管其很常见,但现有的面部发红量化工具在临床实用性和易用性方面存在局限。

目的

开发一种高性能的发红量表。

方法

本研究介绍了凯斯蒂发红量表(KRS),概述了其开发和验证过程,并讨论了其潜在的临床应用。

结果

研究者们认为该量表有用且易于使用,大多数人表示会在临床实践中使用它来记录患者特征。利用Gwet's AC2、肯德尔W系数、斯皮尔曼ρ系数、加权科恩kappa系数和布兰德-奥特曼分析进行评估的结果——显示出强烈的序数一致性、稳健的秩一致性和可忽略的偏差——表明这个新的评分系统在0至3级量表上测量皮肤色素沉着既可靠又有效。

结论

KRS是一种可靠、易于使用的工具,可增强皮肤科对面部发红的评估。通过专家评估和统计分析对其进行验证,凸显了其改善临床实践和研究的潜力。

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The Kesty Hyperpigmentation Scale: A Study to Validate a New Tool for Assessing Facial Hyperpigmentation.凯斯蒂色素沉着量表:一项验证用于评估面部色素沉着新工具的研究。
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本文引用的文献

1
The effects of long-pulsed alexandrite laser therapy on facial redness and skin microbiota compositions in rosacea: A prospective, multicentre, single-arm clinical trial.长脉冲翠绿宝石激光治疗酒渣鼻面部红斑和皮肤微生物群组成的疗效:一项前瞻性、多中心、单臂临床试验。
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Diagnosing Disorders of Facial Erythema.诊断面部红斑障碍。
Dermatol Clin. 2023 Jul;41(3):377-392. doi: 10.1016/j.det.2023.02.004. Epub 2023 Apr 18.
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Intense pulsed light treatment for inflammatory skin diseases: a review.强脉冲光治疗炎症性皮肤病:综述。
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Rosacea management: A comprehensive review.酒渣鼻管理:全面综述。
J Cosmet Dermatol. 2022 May;21(5):1895-1904. doi: 10.1111/jocd.14816. Epub 2022 Feb 14.
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Treatment protocols and efficacy of light and laser treatments in post-acne erythema.光疗和激光治疗痤疮后红斑的治疗方案和疗效。
J Cosmet Dermatol. 2022 Feb;21(2):648-656. doi: 10.1111/jocd.14729. Epub 2022 Jan 5.
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Evaluation of a simple image-based tool to quantify facial erythema in rosacea during treatment.评估一种简单的基于图像的工具,用于在治疗玫瑰痤疮期间量化面部红斑。
Skin Res Technol. 2020 Nov;26(6):804-812. doi: 10.1111/srt.12878. Epub 2020 Jun 14.
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Noninvasive objective skin measurement methods for rosacea assessment: a systematic review.用于酒渣鼻评估的非侵入性客观皮肤测量方法:一项系统综述。
Br J Dermatol. 2020 Jan;182(1):55-66. doi: 10.1111/bjd.18151. Epub 2019 Aug 18.
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Use of an alternative method to evaluate erythema severity in a clinical trial: difference in vehicle response with evaluation of baseline and postdose photographs for effect of oxymetazoline cream 1·0% for persistent erythema of rosacea in a phase IV study.在临床试验中评估红斑严重程度的替代方法:在一项评估基线和用药后照片的研究中,观察 4 期试验中 1.0%盐酸奥洛他定乳膏治疗酒渣鼻持续性红斑的疗效,观察到赋形剂反应的差异。
Br J Dermatol. 2019 May;180(5):1050-1057. doi: 10.1111/bjd.17462. Epub 2019 Feb 27.
9
Quantification of skin erythema response to topical alcohol in alcohol-intolerant East Asians.
Skin Res Technol. 2017 Nov;23(4):593-596. doi: 10.1111/srt.12376. Epub 2017 May 17.
10
Assessment of rosacea severity: A review of evaluation methods used in clinical trials.玫瑰痤疮严重程度评估:临床试验中使用的评估方法综述。
J Am Acad Dermatol. 2015 Jul;73(1):138-143.e4. doi: 10.1016/j.jaad.2015.02.1121. Epub 2015 Mar 19.