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凯斯蒂色素沉着量表:一项验证用于评估面部色素沉着新工具的研究。

The Kesty Hyperpigmentation Scale: A Study to Validate a New Tool for Assessing Facial Hyperpigmentation.

作者信息

Kesty Chelsea E, Kesty Katarina R

机构信息

St. Petersburg Skin and Laser, St. Petersburg, Florida, USA.

Kesty AI, St. Petersburg, Florida, USA.

出版信息

J Cosmet Dermatol. 2025 Apr;24(4):e70055. doi: 10.1111/jocd.70055.

DOI:10.1111/jocd.70055
PMID:40167296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11960423/
Abstract

BACKGROUND

Facial hyperpigmentation due to sun damage, post-inflammatory hyperpigmentation, and other factors is a common complaint of patients. While lasers and topical treatments are frequently used to manage hyperpigmentation, a standardized way of measuring response to treatment is difficult.

AIMS

The Kesty Hyperpigmentation Scale (KHS) is a novel clinical instrument created to provide a consistent approach for evaluating facial hyperpigmentation in both cosmetic dermatology and broader medical settings.

METHODS

This study introduces the KHS, describes the process of its creation and validation, and examines its practical uses in clinical settings. Statistical analysis included Gwet's AC2, Kendall's W, Spearman's ρ/rho, weighted Cohen's kappa, and Bland-Altman analysis.

RESULTS

The findings of the statistical analysis included high ordinal agreement, strong rank concordance, and minimal bias. This supports the conclusion that the novel rating approach is both reliable and valid for assessing skin hyperpigmentation on the given 0-3 scale. The KHS offers an objective framework to measure the severity of hyperpigmentation, helping clinicians track patient progress after cosmetic treatments, and fostering improved communication with patients. Participants in this study found the scale to be user-friendly, and the majority expressed interest in incorporating it into their practices to document patient conditions.

CONCLUSIONS

The KHS is an effective and user-friendly tool for evaluating facial hyperpigmentation, addressing a significant need within dermatology.

摘要

背景

因阳光损伤、炎症后色素沉着及其他因素导致的面部色素沉着是患者常见的诉求。虽然激光和局部治疗常用于处理色素沉着,但难以找到一种标准化的方法来衡量治疗反应。

目的

凯斯蒂色素沉着量表(KHS)是一种新型临床工具,旨在为美容皮肤科及更广泛的医疗环境中评估面部色素沉着提供一种一致的方法。

方法

本研究介绍了KHS,描述了其创建和验证过程,并考察了其在临床环境中的实际应用。统计分析包括格韦特AC2、肯德尔W、斯皮尔曼ρ/相关系数、加权科恩kappa及布兰德-奥特曼分析。

结果

统计分析结果包括高度的有序一致性、强烈的秩相关性和最小偏差。这支持了以下结论:这种新型评分方法在给定的0至3分量表上评估皮肤色素沉着既可靠又有效。KHS提供了一个客观框架来衡量色素沉着的严重程度,有助于临床医生跟踪美容治疗后患者的进展情况,并促进与患者的沟通改善。本研究中的参与者发现该量表使用方便,大多数人表示有兴趣将其纳入实践中以记录患者病情。

结论

KHS是一种评估面部色素沉着的有效且用户友好的工具,满足了皮肤科的一项重大需求。

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JAMA Dermatol. 2024 Feb 1;160(2):239-240. doi: 10.1001/jamadermatol.2023.5470.
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The 675-nm wavelength for treating facial melasma.675nm 波长治疗面部黄褐斑。
Skin Res Technol. 2023 Aug;29(8):e13434. doi: 10.1111/srt.13434.
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Disorders of Facial Hyperpigmentation.面部色素沉着障碍。
Dermatol Clin. 2023 Jul;41(3):393-405. doi: 10.1016/j.det.2023.02.005. Epub 2023 Apr 14.
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Dermatology: how to manage facial hyperpigmentation in skin of colour.皮肤病学:如何处理有色人种皮肤的面部色素沉着。
Drugs Context. 2022 May 31;11. doi: 10.7573/dic.2021-11-2. eCollection 2022.
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Treatment of hyperpigmentation after burn: A literature review.烧伤后色素沉着的治疗:文献综述。
Burns. 2022 Aug;48(5):1055-1068. doi: 10.1016/j.burns.2022.04.017. Epub 2022 Apr 25.
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Tranexamic acid versus fractional carbon dioxide laser in post-acne hyperpigmentation.氨甲环酸与二氧化碳点阵激光治疗痤疮后色素沉着的对比
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Lasers Med Sci. 2020 Sep;35(7):1599-1606. doi: 10.1007/s10103-020-03008-z. Epub 2020 Apr 17.
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The Safety and Efficacy of Treatment With a 1,927-nm Diode Laser With and Without Topical Hydroquinone for Facial Hyperpigmentation and Melasma in Darker Skin Types.1927纳米二极管激光联合或不联合外用氢醌治疗深色皮肤类型面部色素沉着和黄褐斑的安全性和有效性。
Dermatol Surg. 2018 Oct;44(10):1304-1310. doi: 10.1097/DSS.0000000000001521.
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