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Phase II trial of elliptinium in advanced renal cell carcinoma.

作者信息

Caillé P, Mondesir J M, Droz J P, Kerbrat P, Goodman A, Ducret J P, Theodore C, Spielman M, Rouëssé J, Amiel J L

出版信息

Cancer Treat Rep. 1985 Jul-Aug;69(7-8):901-2.

PMID:4016798
Abstract

Forty patients with advanced renal cell carcinoma were treated with elliptinium by a weekly infusion of 100 mg/m2. Of 38 evaluable patients, five had an objective response (13.2%). Average response duration was 8 months (range, 5-11). The major dose-limiting toxic effect was induction of antielliptinium antibodies, with the risk of intravascular hemolysis. Elliptinium has modest activity in advanced renal cell cancer and does not produce myelosuppression.

摘要

相似文献

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Phase II trial of elliptinium in advanced renal cell carcinoma.
Cancer Treat Rep. 1985 Jul-Aug;69(7-8):901-2.
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