古斯塔夫-鲁西研究所成人转移性肾细胞癌化疗的十二年经验
Twelve-year experience with chemotherapy in adult metastatic renal cell carcinoma at the Institut Gustave-Roussy.
作者信息
Droz J P, Theodore C, Ghosn M, Lupera H, Piot G, De Forges A, Klink M, Rouesse J, Amiel J L
机构信息
Medical Department, Institut Gustave-Roussy, Villejuif, France.
出版信息
Semin Surg Oncol. 1988;4(2):97-9.
One hundred fifty-three adult patients with metastatic renal carcinoma were treated over a 12-year period. Five successive chemotherapeutic protocols were used: vincristine or teniposide plus CCNU, elliptinium weekly or monthly, ifosfamide, and lastly, a multidrug regimen with adriamycin, vindesine, cyclophosphamide, cisplatinum, and dacarbazine. Results obtained with these different consecutive protocols were very disappointing with only ten (7%) objective responses encountered.
在12年期间，对153例转移性肾癌成年患者进行了治疗。采用了五种连续的化疗方案：长春新碱或替尼泊苷加洛莫司汀、每周或每月使用丙脒腙、异环磷酰胺，最后是采用多柔比星、长春地辛、环磷酰胺、顺铂和达卡巴嗪的多药方案。这些不同的连续方案所获得的结果非常令人失望，仅出现了10例（7%）客观缓解。
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