Zhong Dahui, Liu Yang, Mo Lin, Zhang Li, Shen Xuelan, Xiang Qiumeng
Endoscopy Center, Children's Hospital of Chongqing Medical University, Chongqing, China.
Department of Nursing, Children's Hospital of Chongqing Medical University, Chongqing, China.
PLoS One. 2025 Apr 1;20(4):e0320790. doi: 10.1371/journal.pone.0320790. eCollection 2025.
This study aimed to establish an intelligent management platform for home medication for children with leukemia and verify its efficacy in enhancing home medication compliance in children with leukemia using intelligent approaches.
Children with leukemia who were treated in a hospital in Chongqing, China, between January and April 2022 were enrolled. The user intentions and requirements for an intelligent management platform for home medication were analyzed for both the patient and their family, leading to the establishment of an intelligent management platform with multiple ports. Children with leukemia who were at the maintenance stage of the treatment during July-December 2023, were randomly divided into control and experimental groups. For medication management, hard copies of chemotherapy records and regular outpatient follow-up data were collected from both groups. For the experimental group, data were also acquired from the intelligent management platform. The self-efficacy in rational medication, rate of missed/incorrect administration, and unplanned admission rate of the two groups were assessed after three months of intervention. The usage efficiency of the platform was also evaluated in children and caregivers in the experimental group.
The intelligent management platform for home medication for children with leukemia comprised a patient-end WeChat applet, a medical staff-end WeChat applet, and a Web management end, with each applet having distinct functions. After three months of intervention, the self-efficacy score in rational medication of the experimental group was significantly higher than that of the control group (33.93 vs. 30.03, P < 0.05). Furthermore, the rate of missed or incorrect administration of the experimental group was significantly lower than that of the control group (10% vs. 26.76%, P < 0.05). The rates of unplanned admission of the two groups did not differ significantly (P > 0.05). Moreover, the overall satisfaction of the experimental group of children and caregivers with the proposed platform was 94.29%.
The proposed management platform for home medication for children with leukemia was associated with increased self-efficacy in the rational medication of these children and a reduced missed/incorrect administration rate, thereby providing an effective approach for more accurate and safer home medication for these children.
本研究旨在建立一个针对白血病患儿居家用药的智能管理平台，并验证其采用智能方法提高白血病患儿居家用药依从性的效果。
纳入2022年1月至4月在中国重庆某医院接受治疗的白血病患儿。分析了患者及其家属对居家用药智能管理平台的用户意图和需求，从而建立了一个多端口的智能管理平台。将2023年7月至12月处于治疗维持阶段的白血病患儿随机分为对照组和实验组。对于用药管理，从两组收集化疗记录硬拷贝和定期门诊随访数据。对于实验组，还从智能管理平台获取数据。干预三个月后，评估两组的合理用药自我效能感、漏服/误服率和非计划入院率。还对实验组的儿童和照顾者评估了平台的使用效率。
白血病患儿居家用药智能管理平台包括患者端微信小程序、医护人员端微信小程序和网络管理端，每个小程序都有不同的功能。干预三个月后，实验组的合理用药自我效能感得分显著高于对照组（33.93对30.03，P<0.05）。此外，实验组的漏服或误服率显著低于对照组（10%对26.76%，P<0.05）。两组的非计划入院率无显著差异（P>0.05）。此外，实验组的儿童和照顾者对所提出平台的总体满意度为94.29%。
所提出的白血病患儿居家用药管理平台与这些患儿合理用药的自我效能感增加和漏服/误服率降低相关，从而为这些患儿更准确、更安全的居家用药提供了一种有效方法。
