Endoscopy Center, Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Department of Children Healthcare, Chongqing Youyoubaobei Women and Children's Hospital, Chongqing, People's Republic of China.
Hematology. 2023 Dec;28(1):2227490. doi: 10.1080/16078454.2023.2227490.
This study aimed to investigate home-based medication adherence in children with acute leukemia and its related factors.
We examined 132 children with acute leukemia in a tertiary pediatric hospital in Chongqing. A general questionnaire, the MMAS-8 (the eight-item Morisky Medication Adherence Scale), SEAMS (Self-efficacy for Appropriate Medication Use Scale), and a multifactorial logistic regression model were used to analyze the factors related to drug adherence of the children.
54.55% of patients showed good medication adherence, while 50.76% either forgot a dose or administered an incorrect dose. The average score on the Self-Efficacy for Appropriate Medication Use Scale (SEAMS) was 32.47.61. The logistic regression analysis revealed that a SEAMS score, the occupation of caregivers, and the patient's age were predictors of medication adherence among pediatric leukemia patients (< 0.05).
The home-based medication adherence in children with acute leukemia was not favorable. Patients with low SEAMS scores, farmers serving as caregivers, and children under the age of three should arouse more attention. It is expected to strengthen the confidence of patient families in medication by emphasizing the development of their relationships with healthcare professionals. Awareness of breakthroughs in leukemia home-based medication management systems by utilizing Internet technology.
本研究旨在探讨急性白血病患儿的居家用药依从性及其相关因素。
我们在重庆一家儿科三甲医院检查了 132 名急性白血病患儿。使用一般问卷、MMAS-8（Morisky 用药依从性量表的 8 项）、SEAMS（适当用药自我效能量表）和多因素逻辑回归模型分析与儿童药物依从性相关的因素。
54.55%的患者表现出良好的用药依从性，而 50.76%的患者要么忘记剂量，要么给予不正确的剂量。适当用药自我效能量表（SEAMS）的平均得分为 32.47.61。逻辑回归分析显示，SEAMS 评分、照顾者的职业和患者年龄是儿科白血病患者用药依从性的预测因素（<0.05）。
急性白血病患儿的居家用药依从性不理想。SEAMS 评分低、农民作为照顾者、三岁以下儿童应引起更多关注。通过强调患者家庭与医疗保健专业人员关系的发展，增强患者家庭对药物治疗的信心。利用互联网技术，提高白血病居家用药管理系统的认识。
