Wang Mengzhen, Zeng Li, Chen Hongjun, Hu Senhao, Huang Chengzhi, Zhen Shujun, Zhan Lei
Key Laboratory of Biomedical Analytics, Chongqing Science and Technology Bureau, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Food Chem. 2025 Jul 30;481:144031. doi: 10.1016/j.foodchem.2025.144031. Epub 2025 Mar 26.
The development of novel preservation techniques capable of food safety and nutrition retention has received extensive attention. Herein, a biocompatible and biodegradable composite folate/zinc supramolecular hydrogel loaded with Ce-doped carbon dots (named FZCC hydrogel) has been fabricated. This hydrogel was synthesized through hydrogen bonds or metal-ligand coordination and held the advantages of superior antibacterial properties, self-healing properties, and washability. Particularly, CeCDs in the hydrogel possessed photodynamic capabilities under white light irradiation, endowing broad antibacterial ability against both Gram-positive and Gram-negative bacteria. The growth inhibition rate reached up to 83.98 % and 80.30 % for S. aureus and E. coli. Moreover, the hydrogels can release high concentrations of Zn over 15 days, resulting in a sustained antimicrobial effect. The application of FZCC hydrogel to pakchoi cabbages, apples, and cooked meat can effectively prolong the shelf life and ensure food quality by controlling microbial contaminations, providing great potential for designing sustainable active food packaging materials.
能够保持食品安全和营养的新型保鲜技术的发展受到了广泛关注。在此，制备了一种负载铈掺杂碳点的生物相容性和可生物降解的复合叶酸/锌超分子水凝胶（命名为FZCC水凝胶）。该水凝胶通过氢键或金属-配体配位合成，具有优异的抗菌性能、自愈性能和可洗性。特别地，水凝胶中的CeCDs在白光照射下具有光动力能力，赋予了对革兰氏阳性菌和革兰氏阴性菌广泛的抗菌能力。金黄色葡萄球菌和大肠杆菌的生长抑制率分别高达83.98%和80.30%。此外，水凝胶可在15天内释放高浓度的锌，产生持续的抗菌效果。将FZCC水凝胶应用于小白菜、苹果和熟肉中，可通过控制微生物污染有效延长保质期并确保食品质量，为设计可持续的活性食品包装材料提供了巨大潜力。
