Nociplastic pain: A practical guide to chronic pain management in the primary care setting.

Management of chronic pain is one of the most challenging medical issues in primary care. Effective pain management requires an understanding of nociplastic pain, a condition characterized by amplification of pain transmission and pain perception. Unlike nociceptive and neuropathic pain, nociplastic pain does not involve visible tissue injury or damage, which makes it difficult to understand and manage. This review discusses practical ways for primary care clinicians to identify and manage nociplastic pain at the point of care.