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角膜塑形术对调节期间周边屈光的影响。

The influence of orthokeratology on peripheral refraction during accommodation.

作者信息

Li Zhixing, Jin Xia, Gui Mengfang, Zhang Xiaojin, Guo Xiaohong, Pan Tonghe, Wang Ying

机构信息

Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, 315000, China.

School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.

出版信息

BMC Ophthalmol. 2025 Apr 1;25(1):161. doi: 10.1186/s12886-025-03985-1.

Abstract

SIGNIFICANCE

The change in peripheral refraction from hyperopic to myopic defocus following orthokeratology (OK) has been recognized as a main factor in myopia control. However, the impact of OK lenses on peripheral refraction at nearpoints in myopic eyes still requires further investigation.

PURPOSE

This study aims to investigate changes in peripheral refraction during accommodation in myopic adults after orthokeratology (OK) wear.

METHODS

Twenty-four selected myopic adults (mean spherical equivalent: -2.70 ± 1.04 D) participated in this study. Peripheral refractions were measured by an auto-refractor with targets located at 25 cm and 50 cm from the eye. Measurements were performed across ± 30º of the horizontal field in 5º steps from the visual axis of subject's right eye before and after wearing the OK lens. The statistical package SPSS was used to analyze the data to determine the relationship between peripheral refractions and accommodation.

RESULTS

After wearing the OK lens, the peripheral refraction became more myopic with increasing eccentricity during accommodation (t > 2.80, p < 0.01, N30º, N25º, N20º, T15º, T20º, T25º and T30º, for 25 cm and 50 cm). While relative hyperopic reflective errors were observed in the central (accommodative lag) and near peripheral (= < 15 º) retinal fields (t < -2.5, p < 0.02, for 0º, N5º, N10º, N15º and T10º for 25 cm and 50 cm), relative myopic refractive errors were evident in the farther periphery (> 15 º). (for 25 cm, -0.45 ± 1.18, -0.71 ± 1.47, -1.00 ± 1.31 and -1.70 ± 2.16D, for N30º, T20º, T25º, and T30º; for 50 cm, -0.76 ± 1.28, -0.84 ± 1.05; -1.17 ± 1.30 and -2.15 ± 1.81D, for N30º, T20º, T25º, and T30º; t > 2.5, P < 0.02).

CONCLUSION

The myopic shift of peripheral refraction from the OK lens was partly counteracted by an insufficient change in refractive power of the eye during accommodation. Even though the refractive errors become relative hyperopic in the central and near peripheral retinal fields, relative myopic refraction was still maintained in the farther periphery for the accommodated myopic eyes treated with OK lenses.

摘要

意义

角膜塑形术(OK)后周边屈光从远视性离焦变为近视性离焦的变化已被认为是控制近视的主要因素。然而,OK镜片对近视眼近点周边屈光的影响仍需进一步研究。

目的

本研究旨在调查近视成年人佩戴角膜塑形术(OK)后在调节过程中周边屈光的变化。

方法

24名选定的近视成年人(平均等效球镜度:-2.70±1.04D)参与了本研究。使用自动验光仪测量周边屈光,测量目标位于距眼睛25cm和50cm处。在佩戴OK镜片前后,从受试者右眼视轴开始,以5°步长在水平视野±30°范围内进行测量。使用统计软件包SPSS分析数据,以确定周边屈光与调节之间的关系。

结果

佩戴OK镜片后,在调节过程中,随着偏心度增加,周边屈光变得更加近视(t>2.80,p<0.01,对于25cm和50cm处的N30°、N25°、N20°、T15°、T20°、T25°和T30°)。虽然在中央(调节滞后)和近周边(<=15°)视网膜区域观察到相对远视性屈光不正(t<-2.5,p<0.02,对于25cm和50cm处的0°、N5°、N10°、N15°和T10°),但在更远的周边(>15°)相对近视性屈光不正明显(对于25cm,N30°、T20°、T25°和T30°分别为-0.45±1.18、-0.71±1.47、-1.00±1.31和-1.70±2.16D;对于50cm,N30°、T20°、T25°和T30°分别为-0.76±1.28、-0.84±1.05、-1.17±1.30和-2.15±1.81D;t>2.5,P<0.02)。

结论

OK镜片引起的周边屈光近视性偏移在一定程度上被调节过程中眼睛屈光力变化不足所抵消。尽管在中央和近周边视网膜区域屈光不正变为相对远视性,但对于接受OK镜片治疗的调节性近视眼,在更远的周边仍保持相对近视性屈光。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecfd/11959750/af36b8db24da/12886_2025_3985_Fig1_HTML.jpg

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