Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China; Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Cont Lens Anterior Eye. 2022 Aug;45(4):101532. doi: 10.1016/j.clae.2021.101532. Epub 2021 Nov 1.
This prospective study assessed the influence of wearing and then discontinuing orthokeratology (OK) lenses on retinal shape and peripheral refraction in myopic children.
Fifty-eight myopic children (age 8-12 years) were equally divided into an OK group and a single vision spectacles (SVS) group. After 12 months of OK, it was discontinued for 1 month. Peripheral eye length (PEL), relative peripheral refraction (RPR), and corneal parameters were measured in the right eye on the nasal and temporal retinal sides at baseline, 6 months, and 12 months (13 months in OK group) visits.
In the SVS group, faster elongation of the temporal side PEL made the eyes more asymmetric and prolate, developing a temporal pointed shape. In the OK group, the nasal retinal side PEL grew faster, the nasal RPR developed less hyperopic defocus, and the eye shape became more symmetric and less prolate. The central cornea became thinner and flattened, while the peripheral cornea became steeper. Changes in corneal thickness, relative peripheral corneal power, and K-values were no significant differences for the OK and SVS groups at 12 months.
The cornea reverted to be no difference with myopic children with SVS after 1 month discontinuation of OK. The retinal shape of SVS eyes became more asymmetric and prolate with myopia progression. OK remodelled retinal shape to be less asymmetric and less prolate.
本前瞻性研究评估了佩戴角膜塑形镜(OK)后再停戴对近视儿童视网膜形状和周边屈光度的影响。
将 58 名近视儿童(8-12 岁)平均分为 OK 组和单焦框架眼镜(SVS)组。OK 治疗 12 个月后停戴 1 个月。分别于基线、6 个月和 12 个月(OK 组为 13 个月)时测量右眼鼻侧和颞侧视网膜周边眼长(PEL)、相对周边屈光度(RPR)和角膜参数。
SVS 组颞侧 PEL 增长较快,使眼球更加不对称和长轴化,呈颞侧尖锐形状。OK 组鼻侧视网膜侧 PEL 生长较快,鼻侧 RPR 形成较少的远视离焦,眼形更加对称,长轴化程度较低。中央角膜变薄变平,而周边角膜变陡。OK 和 SVS 组在 12 个月时,角膜厚度、相对周边角膜屈光力和 K 值的变化均无统计学差异。
停戴 OK 1 个月后,角膜形状与佩戴 SVS 的近视儿童无差异。SVS 眼的视网膜形状随近视进展变得更加不对称和长轴化。OK 重塑了视网膜形状,使其变得不那么不对称和长轴化。