Milot Marie-Hélène, Palimeris Stephania, Shahzad Yavuz, Corriveau Hélène, Tremblay François, Boudrias Marie-Hélène
Faculté de médecine et des sciences de la santé, Université de Sherbrooke, École de réadaptation, Sherbrooke, Québec, Canada.
Centre de recherche sur le vieillissement, CIUSSS de l'Estrie-CHUS, Sherbrooke, Québec, Canada.
J Rehabil Med Clin Commun. 2025 Mar 24;8:42941. doi: 10.2340/jrm-cc.v8.42941. eCollection 2025.
We showed that a tailored strengthening intervention based on the size of motor evoked potentials (MEPs) in the affected arm was effective in improving function in chronic stroke survivors. Here, we investigated whether the short-term gains in arm function were maintained at 1-year follow-up.
Twenty-five participants at the chronic stage of a stroke.
Participants were classified in the light (LI; MEPs 50-120 μV, = 8) and high (HI; MEPs > 120μV, = 17) intensity training groups. The strengthening protocol consisted of adjusted exercises for the affected arm (3X/week; 4 weeks). The Fugl-Meyer Stroke Assessment (FMA), Grip strength (GS) and Box and Block test (BBT) were assessed at baseline, post-intervention and at 1-year follow-up. Changes in clinical measures were compared using repeated-measures ANOVA.
A significant effect of time was noted on all outcome measures [FMA: < 0.001; BBT: = 0.05; GS: < 0.001], but the LI group improved more on the FMA ( = 0.003) and maintained their gains at 1-year follow-up ( = 0.527) than the HI group.
The size of MEPs in the affected arm could be a significant factor in influencing responses to strengthening exercises post-stroke and allow gains to be maintained up to 1 year post-intervention.
我们已证明，基于患侧手臂运动诱发电位（MEP）大小的定制强化干预措施，对于改善慢性卒中幸存者的功能是有效的。在此，我们研究了手臂功能的短期改善在1年随访期内是否得以维持。
25名处于卒中慢性期的参与者。
参与者被分为低强度（LI；MEP为50 - 120μV，n = 8）和高强度（HI；MEP > 120μV，n = 17）训练组。强化方案包括针对患侧手臂的调整练习（每周3次；共4周）。在基线、干预后和1年随访时评估Fugl - Meyer卒中评估量表（FMA）、握力（GS）和箱块测试（BBT）。使用重复测量方差分析比较临床指标的变化。
在所有结局指标上均观察到时间的显著影响[FMA：p < 0.001；BBT：p = 0.05；GS：p < 0.001]，但LI组在FMA上改善更多（p = 0.003），且在1年随访时维持了改善效果（p = 0.527），优于HI组。
患侧手臂MEP的大小可能是影响卒中后强化训练反应的一个重要因素，并且能使干预后长达1年的改善效果得以维持。
