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巴西静脉血栓栓塞住院率的时间趋势。

Temporal trend in venous thromboembolism hospitalization rates in Brazil.

作者信息

Soares Oliveira Portela Felipe, Wolosker Nelson, Louzada Andressa Cristina Sposato, Portugal Maria Fernanda Cassino, Fiorelli Alexandrino da Silva Marcelo, Lopes Cintra Diogo, Girardi Giulia de Payrebrune St Sève Marins, Fioranelli Alexandre, Teivelis Marcelo Passos

机构信息

Hospital Israelita Albert Einstein, Department of Vascular Surgery - São Paulo (SP), Brazil.

Faculdade Israelita de Ciências da Saúde Albert Einstein - São Paulo (SP), Brazil.

出版信息

Rev Assoc Med Bras (1992). 2025 Mar 31;71(2):e20240608. doi: 10.1590/1806-9282.20240608. eCollection 2025.

Abstract

OBJECTIVE

Venous thromboembolism is a condition of great interest to public health, as it is potentially preventable and has a high morbidity and mortality potential. Knowing the real-world data in a country of continental dimensions such as Brazil is essential to help define health policies that enable proper diagnosis and treatment of this disease. The objective of this study was to evaluate the incidence and in-hospital mortality rates of venous thromboembolism in public hospitals under Brazil's public health system.

METHODS

This is a population-based, cross-sectional, retrospective analysis of all hospitalizations for venous thromboembolism in the Brazilian public health system between 2008 and 2022. Using a public database, all hospital admissions for thromboembolic events were selected, defining the incidence, in-hospital mortality, and differences between Brazilian macro-regions.

RESULTS

A total of 700,315 admissions for venous thromboembolism were documented in the Brazilian public health system between 2008 and 2022, which represents 3.02 admissions per 10,000 inhabitants per year. The Southeast region accounted for more than half (54.5%) of the hospitalizations. The highest incidence of hospitalizations occurred in the wealthiest regions (Southeast and South), while the lowest incidence was observed in the poorest regions (North and Northeast). On the other hand, a higher proportion of in-hospital mortality was observed in the North and Northeast regions.

CONCLUSION

The highest admission rates were registered in wealthier regions, while a higher proportion of deaths was found in the poorer ones. This may reveal the difficulty in accessing healthcare services in the North and Northeast regions, which is reflected in the potential underdiagnosis of thromboembolic events in these regions.

摘要

目的

静脉血栓栓塞是一个备受公共卫生关注的问题,因为它具有潜在可预防性,且发病率和死亡率较高。了解像巴西这样幅员辽阔的国家的真实数据,对于制定有助于对该疾病进行正确诊断和治疗的卫生政策至关重要。本研究的目的是评估巴西公共卫生系统下公立医院中静脉血栓栓塞的发病率和院内死亡率。

方法

这是一项基于人群的横断面回顾性分析,研究对象为2008年至2022年间巴西公共卫生系统中所有因静脉血栓栓塞而住院的病例。利用一个公共数据库,选取所有因血栓栓塞事件而住院的病例,确定发病率、院内死亡率以及巴西各宏观区域之间的差异。

结果

2008年至2022年间,巴西公共卫生系统共记录了700315例静脉血栓栓塞住院病例,相当于每年每10000名居民中有3.02例住院病例。东南部地区的住院病例占比超过一半(54.5%)。住院率最高的地区是最富裕的地区(东南部和南部),而最低的发病率则出现在最贫困的地区(北部和东北部)。另一方面,北部和东北部地区的院内死亡率较高。

结论

富裕地区的住院率最高,而贫困地区的死亡比例更高。这可能揭示了北部和东北部地区在获得医疗服务方面存在困难,这反映在这些地区血栓栓塞事件可能存在诊断不足的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b47/11964315/22ab9fad6b0f/1806-9282-ramb-71-02-e20240608-gf01.jpg

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