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复苏室中多发伤和/或重伤患者的影像学检查策略:系统评价与临床实践指南更新

Imaging strategies for patients with multiple and/or severe injuries in the resuscitation room: a systematic review and clinical practice guideline update.

作者信息

Huber-Wagner Stefan, Braunschweig Rainer, Kildal Daniela, Bieler Dan, Prediger Barbara, Hertwig Miriam, Kugler Charlotte, Reske Stefan, Wurmb Thomas, Achatz Gerhard, Friemert Benedikt, Schoeneberg Carsten

机构信息

Department of Trauma Surgery, Schwäbisch Hall Diakonie Hospital, Schwäbisch Hall, Germany.

Institut of Radiology, University Erlangen, Germany, Member of the Board of the Working Group On Musculoskeletal Imaging (AG MSK) of the German Radiological Society, Berlin, Germany.

出版信息

Eur J Trauma Emerg Surg. 2025 Apr 2;51(1):158. doi: 10.1007/s00068-025-02840-8.

Abstract

PURPOSE

Our aim was to develop new evidence-based and consensus-based recommendations for imaging strategies in patients with multiple and/or severe injuries in the resuscitation room. This guideline topic is part of the 2022 update of the German Guideline on the Treatment of Patients with Multiple and/or Severe Injuries.

METHODS

MEDLINE and Embase were systematically searched to August 2021.

INCLUSION CRITERIA

patients with multiple and/or severe injuries in the resuscitation room, randomised controlled trials, prospective cohort studies, cross-sectional studies, and comparative registry studies; comparison of interventions for imaging strategies; patient-relevant clinical outcomes such as diagnostic test accuracy and mortality. Further literature reports were obtained from clinical experts. We considered patient-relevant clinical outcomes such as diagnostic test accuracy and mortality. Risk of bias was assessed using NICE 2012 checklists. The evidence was synthesised narratively, and expert consensus was used to develop recommendations and determine their strength.

RESULTS

Twenty-one studies with a total of 55,227 patients were identified. There were studies with low risk (n = 2), high risk (n = 5) and unclear risk of bias (n = 14). Relevant topics were sonographic imaging of the chest and abdomen (n = 8 studies), X-ray of the chest (n = 1), indications for whole-body computed tomography (n = 6), CT scanner location (n = 1), whole-body computed tomography in haemodynamically unstable patients (n = 3), and prehospital sonography (n = 2). There were studies with low risk (n = 2), high risk (n = 5) and unclear risk of bias (n = 14). One new recommendation was developed, six were modified. All achieved strong consensus.

CONCLUSION

While extended focused assessment with sonography for trauma should be performed for diagnostic purposes after blunt and/or penetrating thoracic and/or abdominal trauma as part of the primary survey in the resuscitation room, whole-body computed tomography (WBCT) gains highest importance as part of the diagnostic procedures for severely injured patients. WBCT with a trauma-specific protocol must be performed in a timely manner if the patient does not require an immediate intervention. Magnetic resonance imaging can be indicated as a further primary diagnostic tool for specific conditions. Two studies were judged to be of low risk of bias in all domains. The risk of selection bias was high in two studies and unclear in seven studies.

摘要

目的

我们的目标是为复苏室中多发伤和/或重伤患者的影像学检查策略制定新的基于证据和共识的建议。本指南主题是《德国多发伤和/或重伤患者治疗指南》2022年更新的一部分。

方法

系统检索了截至2021年8月的MEDLINE和Embase数据库。

纳入标准

复苏室中多发伤和/或重伤患者、随机对照试验、前瞻性队列研究、横断面研究和比较登记研究;影像学检查策略干预措施的比较;与患者相关的临床结局,如诊断检查准确性和死亡率。通过临床专家获取了更多文献报告。我们考虑了与患者相关的临床结局,如诊断检查准确性和死亡率。使用英国国家卫生与临床优化研究所(NICE)2012年清单评估偏倚风险。对证据进行叙述性综合,并利用专家共识制定建议并确定其强度。

结果

共纳入21项研究,涉及55227例患者。其中低风险偏倚的研究有2项,高风险偏倚的研究有5项,偏倚风险不明确的研究有14项。相关主题包括胸部和腹部的超声成像(8项研究)、胸部X线检查(1项研究)、全身计算机断层扫描(CT)的适应证(6项研究)、CT扫描仪位置(1项研究)、血流动力学不稳定患者的全身CT检查(3项研究)和院前超声检查(2项研究)。低风险偏倚的研究有2项,高风险偏倚的研究有5项,偏倚风险不明确的研究有14项。制定了1项新建议,修改了6项建议。所有建议均达成了强烈共识。

结论

在复苏室进行初级评估时,钝性和/或穿透性胸腹部创伤后,为诊断目的应进行扩展创伤超声重点评估(eFAST),而全身CT扫描作为重伤患者诊断程序的一部分最为重要。如果患者不需要立即干预,必须及时进行采用创伤专用方案的全身CT扫描。磁共振成像可作为特定情况的进一步主要诊断工具。两项研究在所有领域的偏倚风险均被判定为低风险。两项研究的选择偏倚风险高,七项研究的选择偏倚风险不明确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2864/11965254/20db96ac33c0/68_2025_2840_Fig1_HTML.jpg

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