Koubi H, Fréminet A
Comp Biochem Physiol B. 1985;81(1):103-10. doi: 10.1016/0305-0491(85)90168-3.
Glycogen content (mg/g) and stores (mg) were determined in 3- and 7-month-old obese and lean Zucker rats, under fed and fasted (48 hr) conditions. Hepatic content was higher in fed obese than in lean rats (3 months: 90 vs 70; 7 months: 107 vs 74); it was exhausted after fasting in lean but decreased by 56% in obese rats. Muscle content in fed obese and lean animals did not differ; it decreased comparably after fasting. Myocardial content was higher in fed obese than lean rats (3 months: 7.2 vs 3.6; 7 months: 7.5 vs 6.3); it was enhanced with fasting (10.0 vs 7.5). Total glycogen stores were higher in obese than in lean animals (3 months: 2500 vs 1400; 7 months: 4000 vs 2000) because of the hepatic store. The discussion includes a comparison with available data, taking into account methodological aspects, lipid stores and the FFA/carbohydrate interrelationship.
在进食和禁食（48小时）条件下，测定了3月龄和7月龄肥胖及瘦型Zucker大鼠的糖原含量（毫克/克）和储存量（毫克）。进食的肥胖大鼠肝脏糖原含量高于瘦大鼠（3个月时：90对70；7个月时：107对74）；禁食后，瘦大鼠肝脏糖原耗尽，而肥胖大鼠肝脏糖原减少了56%。进食的肥胖和瘦型动物肌肉糖原含量无差异；禁食后两者均有类似程度的下降。进食的肥胖大鼠心肌糖原含量高于瘦大鼠（3个月时：7.2对3.6；7个月时：7.5对6.3）；禁食后心肌糖原含量增加（10.0对7.5）。由于肝脏糖原储存，肥胖动物的总糖原储存量高于瘦动物（3个月时：2500对1400；7个月时：4000对2000）。讨论内容包括结合方法学、脂质储存以及游离脂肪酸/碳水化合物相互关系等方面，与现有数据进行比较。
