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镁质与钛质无头加压螺钉用于固定Hoffa型骨折的生物力学体外研究

Magnesium versus titanium headless compression screws for fixation of a Hoffa-type fracture - a biomechanical in-vitro study.

作者信息

Felten Larissa, Migliorini Filippo, Hildebrand Frank, Weber Christian David

机构信息

RWTH Aachen University, 52074, Aachen, Germany.

Department of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.

出版信息

BMC Musculoskelet Disord. 2025 Apr 2;26(1):321. doi: 10.1186/s12891-025-08559-2.

Abstract

BACKGROUND

Intraarticular (e.g., Hoffa-type) fractures are usually stabilized with titanium screws, which may necessitate later implant removal. The aim of this study was to compare the biomechanical strength and stability of magnesium and titanium screws.

METHODS

18 double-layer bone blocks were fixed with 18 one-layer bone blocks and divided into 2 groups based on the fixation method: magnesium screw fixation (Magnesium group, n = 9) and traditional titanium screw (Titanium group, n = 9). Compressive force was applied to the specimens orthogonally to the screw axis. First, axial stiffness was measured, and a cyclic loading test was performed, after 10, 100, 1000 and 10,000 cycles respectively, and the axial displacements were recorded. Finally, the specimens were loaded to failure.

RESULTS

There were significant differences between the groups with respect to axial stiffness and cyclic loading. The ultimate failure load was comparable. The average axial stiffness for the magnesium group was 326 ± 67 N/mm and for the titanium group 266 ± 72 N/mm (p = 0.031). The axial displacement relative to 100 N preload after 10,000 cycles in the magnesium group was 1.7319 ± 0.2261 mm and in the titanium group 2.6932 ± 0.5921 mm (p < 0.001). The average ultimate failure in the magnesium group was 920 ± 55 N and in the titanium group 944 ± 40 N (p = 0.293).

CONCLUSIONS

Based on the results magnesium screws show at least a comparable strength and stability as titanium screws in this setting. This study provides support from a biomechanical perspective for the use of magnesium screws in Hoffa fractures.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

关节内(如Hoffa型)骨折通常用钛螺钉固定,这可能需要后期取出植入物。本研究的目的是比较镁螺钉和钛螺钉的生物力学强度和稳定性。

方法

将18个双层骨块与18个单层骨块固定,并根据固定方法分为2组:镁螺钉固定组(镁组,n = 9)和传统钛螺钉组(钛组,n = 9)。垂直于螺钉轴线对标本施加压缩力。首先,测量轴向刚度,并分别在10、100、1000和10000次循环后进行循环加载试验,记录轴向位移。最后,对标本加载直至破坏。

结果

两组在轴向刚度和循环加载方面存在显著差异。极限破坏载荷相当。镁组的平均轴向刚度为326±67N/mm,钛组为266±72N/mm(p = 0.031)。镁组在10000次循环后相对于100N预载荷的轴向位移为1.7319±0.2261mm,钛组为2.6932±0.5921mm(p < 0.001)。镁组的平均极限破坏载荷为920±55N,钛组为944±40N(p = 0.293)。

结论

基于这些结果,在这种情况下,镁螺钉显示出与钛螺钉至少相当的强度和稳定性。本研究从生物力学角度为镁螺钉在Hoffa骨折中的应用提供了支持。

临床试验编号

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c3e/11963631/d31049e0836a/12891_2025_8559_Fig1_HTML.jpg

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